62 citations
,
October 1999 in “Journal of Investigative Dermatology” New mutations in hair keratin genes can change hair structure and cause monilethrix, with nail issues more common in certain gene mutations.
April 2016 in “Journal of Investigative Dermatology” Mutations in the TSPEAR gene cause a new form of ectodermal dysplasia affecting hair and tooth development.
170 citations
,
January 2010 in “animal” Hair follicle growth and fiber production in animals are influenced by chemical signals, proteins, pigmentation, genetics, and nutrients.
February 2026 in “International Journal of Molecular Sciences” PDLLA filler can improve hair thickness and shine by reducing age-related hair decline.
107 citations
,
October 2014 in “PeerJ” Hair's molecular structure is mostly consistent, but genetic differences affect lipid types, which could help diagnose diseases.
57 citations
,
February 2006 in “Journal of Investigative Dermatology” Cylindromas likely originate from hair follicle stem cells, not sweat glands.
20 citations
,
December 1999 in “Journal of Investigative Dermatology” Mutations in the hHb6 gene cause the hair disorder monilethrix.
16 citations
,
November 2020 in “In Vitro Cellular & Developmental Biology - Animal” Microfollicles can effectively model human hair follicles for research and testing.
13 citations
,
September 2022 in “Biomolecules” The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.
8 citations
,
May 2004 in “Textile Research Journal” Scientists made antibodies to tell cashmere and wool apart, which could improve how we identify animal fibers.
3 citations
,
October 2024 in “Frontiers in Medicine” Sun-exposed skin shows different cell activity and gene expression, suggesting targets to prevent skin aging and cancer.
305 citations
,
December 2000 in “The EMBO Journal” Inhibiting Bmp signaling disrupts hair growth and differentiation.
17 citations
,
February 2015 in “Experimental Dermatology” Keratins are crucial for hair strength, and mutations in certain keratin genes cause hair disorders.
14 citations
,
October 2006 in “Journal of Investigative Dermatology” The keratin naming system was updated to include 54 genes, especially for hair-related keratins.
September 2024 in “PubMed” Certain RNAs may help diagnose alopecia areata by affecting keratin genes.
February 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Fluphenazine and iloprost can induce hair growth.
4 citations
,
May 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” ELL is crucial for gene transcription related to skin cell growth.
12 citations
,
August 2018 in “Journal of Dermatological Science” Scientists made stem cells that can grow hair by adding three specific factors to them.
87 citations
,
September 2012 in “Journal of Cell Science” Keratins are crucial for tissue strength, and mutations in keratin genes can lead to various diseases, highlighting the need for targeted therapies.
2 citations
,
January 2020 in “Methods in molecular biology” Scientists created early-stage hair follicles from human skin cells, which could help treat baldness and study hair growth.
1 citations
,
October 1996 in “Journal of Cutaneous Medicine and Surgery” Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.
11 citations
,
February 2018 in “Amino acids” Copper and iron cause keratin damage in hair by converting methionine to homocysteine.
Keratin gel may help repair damaged nerves.
86 citations
,
August 2011 in “Toxicological sciences” TCDD speeds up skin barrier formation by increasing certain gene expressions.
49 citations
,
April 2010 in “International Journal of Cosmetic Science” Hair ages as the cuticle wears down, especially beyond 1 meter from the root, affecting its strength and shine.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Applying the anti-cancer drug Bortezomib to skin can promote hair growth and increase hair proteins through the GATA-3 factor.
6 citations
,
August 2012 in “The Journal of Pediatrics” A 12-year-old girl was diagnosed with monilethrix, a genetic condition causing fragile, beaded hair that breaks easily, with no effective treatment available.
127 citations
,
March 2016 in “PLoS ONE” Key genes and pathways crucial for hair follicle development in cashmere goats were identified, aiding fleece production improvement.
1398 citations
,
May 2008 in “Histochemistry and Cell Biology” Keratins are crucial for cell stability, wound healing, and cancer diagnosis.
15 citations
,
January 2012 in “Journal of Veterinary Science” Different dog breeds have varying skin thickness and protein expression in their skin.