research Transforming Growth Factor-??, Smad, and Collagen Expression Patterns in Fetal and Adult Keratinocytes
Keratinocytes show more TGF-β system activity and collagen production as they age, which might affect wound scarring.
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research Hair of the Dog: Identification of a Cis-Regulatory Module Predicted to Influence Canine Coat Composition
Researchers found a genetic region that influences the number of coat layers in dogs.
research Crosslinking Between Trichocyte Keratins and Keratin Associated Proteins
research The hair shaft: normality, abnormality, and genetics
Hair microscopy is useful for diagnosing hair disorders, but clear definitions are needed for accurate genetic analysis.
research Ultrastructural localization of hair keratins, high sulfur keratin-associated proteins and sulfhydryl oxidase in the human hair
Hair proteins change location and structure as hair cells mature.
research The Molecular Architecture for the Intermediate Filaments of Hardα-Keratin Based on the Superlattice Data Obtained from a Study of Mammals Using Synchrotron Fibre Diffraction
Hard α-keratin has a universal molecular structure with a specific superlattice arrangement.
research Hair Keratin
research De novo filament formation by human hair keratins K85 and K35 follows a filament development pattern distinct from cytokeratin filament networks
Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.
research Review on Herbal Hair Dye
Herbal hair dyes are safer and eco-friendly alternatives to synthetic dyes, offering natural color and hair benefits.
research Investigating the role of keratin proteins and microbial associations in hereditary and pathogenic alopecia
research Peripubertal Testosterone, 17β-Estradiol and Progesterone Concentrations in Hair and Nails in Dobermann Dogs
Hair and nails can show hormone changes during puberty in dogs.
research Skin manifestations of chronic kidney disease
People with advanced chronic kidney disease often have skin problems, which can be treated with various medications and procedures to improve their quality of life.
research Abstracts from the Symposium on the Pathophysiology of Hair Growth Organized by the Institute of Dermatology at the Royal Society of Medicine, 29 October 1987
The symposium concluded that hair growth involves complex processes, including the hair follicle life cycle, the role of the dermal papilla, hair strength, pigmentation, and the impact of diseases and treatments like minoxidil on hair and skin.
research Clinical Snippets
Some cells may slow melanoma growth, a protein could affect skin pigmentation, a gene-silencing method might treat hair defects, skin bacteria changes likely result from eczema, and a defensin protein could help treat multiple sclerosis.
research Estrogens and the hair follicle. Ostrogene und der Haarfollikel
Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.
research 5α-Reductase activity in the human hair follicle concentrates in the dermal papilla
The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
research In Vitro Main Pathways of Steroid Action in Cultured Hair Follicle Cells: Vascular Approach
Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.
research Testosterone Metabolism in Human Skin Cells in vitro and Its Interaction with Estradiol and Dutasteride
Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.
research Mutation of a type II keratin gene (K6a) in pachyonychia congenita
research Multifaceted role of keratins in epithelial cell differentiation and transformation
research Novel mutations in the keratin-74 (KRT74) gene underlie autosomal dominant woolly hair/hypotrichosis in Pakistani families
research The role of integrin alphavbeta6 in impaired wound healing and hair follicle regeneration
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
research Identification of reptilian genes encoding hair keratin-like proteins suggests a new scenario for the evolutionary origin of hair
Reptiles have genes similar to hair proteins, suggesting hair's genetic origins predate mammals.
research Concerted gene duplications in the two keratin gene families
research Complete Structure of an Epithelial Keratin Dimer: Implications for Intermediate Filament Assembly
The study revealed the detailed structure of a keratin dimer, aiding understanding of how intermediate filament proteins function.
research Office Diagnosis of Hair Shaft Defects
The document explains how to identify different hair problems using a microscope.
research Disrupted Ectodermal Organ Morphogenesis in Mice with a Conditional Histone Deacetylase 1, 2 Deletion in the Epidermis
Mice without certain skin proteins had abnormal skin and hair development.
research Analysis of proliferation, apoptosis and keratin expression in cultured normal and immortalized human buccal keratinocytes
SVpgC2a cells show abnormal growth and keratin changes, modeling early cancer development.
research Structural Transition of Trichocyte Keratin Intermediate Filaments During Development in the Hair Follicle
research Non-invasive evaluation of advanced glycation end products in hair as early markers of diabetes and aging
Hair analysis can effectively detect diabetes and aging markers.