34 citations
,
January 2004 in “Genomics” A cluster of 21 keratin-associated protein genes important for hair growth was found on human chromosome 21.
8 citations
,
August 2018 in “Journal of Investigative Dermatology” 5 citations
,
September 2013
January 2013 in “Sen'i Gakkaishi” Microfibrils are key for permanent waves, and hydrolyzed keratin improves wave formation and hair condition.
86 citations
,
May 2002 in “Journal of Investigative Dermatology” A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.
55 citations
,
December 2014 in “Dermatologica sinica/Zhōnghuá pífūkē yīxué zázhì” Keratinocytes control how melanocytes work.
9 citations
,
November 2020 in “The FASEB journal” Intermediate filaments are crucial for cell differentiation and stem cell function.
11 citations
,
September 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.
68 citations
,
August 2014 in “PeerJ” Human hair proteins vary by individual, body site, and ethnicity, useful for forensics.
20 citations
,
December 2012 in “Journal of molecular structure” The study found that thioglycolic acid breaks down hair bonds more consistently than l-cysteine, which is less damaging to hair.
21 citations
,
June 2003 in “Journal of Morphology” Monotreme and marsupial skin proteins show primitive features and species-specific differences compared to placental mammals.
1 citations
,
December 2024 in “Methods in molecular biology” Hair proteins are complex and provide valuable genetic and biological information.
17 citations
,
November 2000 in “Journal of Investigative Dermatology” ZPK helps skin cells mature and may affect skin health.
25 citations
,
August 2020 in “Experimental eye research/Experimental Eye Research” Different types of cells in the eye express specific keratins at various stages of development.
1 citations
,
September 2022 in “River Publishers eBooks” The document concludes that hair keratin-chitosan scaffolds were successfully made and are suitable for biomedical use.
November 2022 in “Research Square (Research Square)” Keratin-associated proteins have ancient origins and were used for different purposes before being adapted for hair in mammals.
92 citations
,
April 1999 in “The journal of investigative dermatology/Journal of investigative dermatology” Nonpalmoplantar skin cells can be made to express keratin 9 by interacting with palmoplantar fibroblasts.
15 citations
,
January 1993 in “DNA sequence” KRT2.13 gene is similar to KRT2.9 but not expressed in hair follicles.
4 citations
,
April 2024 in “The Journal of Cell Biology” Caspase-1 helps hair stem cells move to heal wounded or inflamed skin.
128 citations
,
February 1992 in “British Journal of Dermatology” Basal cell carcinomas likely originate from hair follicle cells or stem cells.
34 citations
,
October 1975 in “Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis” 53 citations
,
June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” KAP genes show significant genetic variability, but its impact on hair traits is unclear.
December 2023 in “Chiwi'saeng'gwa haghoeji” Hair keratin protein might help heal mouth wounds faster.
53 citations
,
June 1983 in “Journal of Investigative Dermatology” The enzyme is crucial for skin cell development and can be activated without proteolytic activation.
58 citations
,
November 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” The Foxn1 gene is essential for normal nail and hair development.
July 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Hair loss in certain mice is linked to changes in keratin-related genes.
December 2022 in “Communications biology” 124 citations
,
November 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.