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research Proliferation and Differentiation of Cultured Human Keratinocytes is Modulated by 1,25(OH)₂D₃ and Synthetic Vitamin D₃ Analogues in a Cell Density‐, Calcium‐ and Serum‐Dependent Manner*

39 citations , January 1997 in “Pharmacology & toxicology”

Vitamin D3 and its analogues affect skin cell growth and development depending on cell density, calcium levels, and serum presence.

research Keratinocytes maintain compartmentalization between dermal papilla and fibroblasts in 3D heterotypic tri‐cultures

16 citations , August 2019 in “Cell Proliferation”

Keratinocytes help keep hair follicle cells and skin cells separate in 3D cultures, which is important for hair growth research.

Short-Term Rho-Associated Kinase Inhibitor Treatment Accelerates Primary Keratinocyte Growth Without Affecting the Stem Cell Population

research 557 Short-term Rho-associated kinase inhibitor treatment accelerates primary keratinocyte growth without affecting the characteristics of the stem cell population

November 2022 in “Journal of Investigative Dermatology”

Short-term treatment with ROCKi increases skin cell growth without changing stem cell features.

research The Simplest Protocol for Rapid and Long-Term Culture of Primary Epidermal Keratinocytes from Human and Mouse

2 citations , January 2019 in “Methods in molecular biology”

A new method helps grow skin cells from humans and mice more easily and quickly.

DermaCult Keratinocyte Expansion Medium: A Serum- and BPE-Free Medium Supporting Long-Term Feeder-Free Expansion of Primary Human Epidermal and Pluripotent Stem Cell-Derived Keratinocytes

research 566 DermaCult™ Keratinocyte Expansion Medium, a Serum- and BPE-free Medium Supporting Long-term Feeder-free Expansion of Primary Human Epidermal and Pluripotent Stem Cell-Derived Keratinocytes

November 2022 in “Journal of Investigative Dermatology”

DermaCult™ Keratinocyte Expansion Medium allows human skin cells to grow longer while keeping their ability to develop properly.

research Dermal papilla cells induce keratinocyte tubulogenesis in culture Elina S. ChermnykhEkaterina A. VorotelyakKsenia Y. Gnedeva • Marianna V. MoldaverYegor E. YegorovAndrey V. Vasiliev •

January 2010

Dermal papilla cells can help form hair-like structures in lab-grown skin cells.

research Establishment and characterization of a canine keratinocyte organoid culture system

34 citations , July 2018 in “Veterinary Dermatology”

A new method to study dog skin diseases using lab-grown skin cells was developed.

research Uptake kinetics and the effect of minoxidil on human keratinocyte cultures.

8 citations , April 1990 in “PubMed”

Minoxidil helps hair growth by prolonging cell division in skin cells.

Conditioned Media Obtained from Human Outer Root Sheath Follicular Keratinocyte Culture Activates Signalling Pathways That Contribute to Maintenance of Hair-Inducing Capacity and Increases Trichogenicity of Cultured Dermal Cells

research Conditioned media obtained from human outer root sheath follicular keratinocyte culture activates signalling pathways that contribute to maintenance of hair-inducing capacity and increases trichogenicity of cultured dermal cells

6 citations , July 2012 in “Experimental Dermatology”

The substance from human hair root cells can help maintain hair growth and make skin cells more capable of growing hair.

research Suppression of Vitamin D Receptor and Induction of Retinoid X Receptor α Expression During Squamous Differentiation of Cultured Keratinocytes

15 citations , March 2000 in “The journal of investigative dermatology/Journal of investigative dermatology”

As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.

research Human hair follicle organ culture: theory, application and perspectives

130 citations , August 2015 in “Experimental Dermatology”

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Mesenchymal Stem Cells Paracrine Proteins From Three-Dimensional Dynamic Culture System Promoted Wound Healing in Third-Degree Burn Models

research Mesenchymal stem cells paracrine proteins from three‐dimensional dynamic culture system promoted wound healing in third‐degree burn models

July 2023 in “Bioengineering & translational medicine”

Mesenchymal stem cell proteins in a special gel improved healing of severe burns.

research Follicular Cell Implantation: An Emerging Cell Therapy for Hair Loss

13 citations , May 2005 in “Seminars in Plastic Surgery”

Follicular Cell Implantation might become a new treatment for hair loss and could lead to advances in organ regeneration.

research A cell-based system for screening hair growth-promoting agents

39 citations , March 2009 in “Archives of Dermatological Research”

Apigenin may help promote hair growth and could treat hair loss.

Induction of Hair Follicle Dermal Papilla Cell Properties in Human Induced Pluripotent Stem Cell-Derived Multipotent LNGFR(+)THY-1(+) Mesenchymal Cells

research Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells

42 citations , February 2017 in “Scientific Reports”

Researchers found a way to create cells from stem cells that act like human cells important for hair growth and could be used for hair regeneration treatments.

research Immunohistochemical detection of cytochrome P450 isoenzymes in cultured human epidermal cells.

19 citations , December 1990 in “Journal of Histochemistry & Cytochemistry”

Foreskin keratinocytes and SVK14 cells express certain cytochrome P450 enzymes, unlike hair follicle keratinocytes.

research Use of primary keratinocyte cultures from plucked human hairs for analysis of gap junctional intercellular communication

3 citations , January 1991 in “Toxicology in Vitro”

Hair follicle cultures are effective for studying cell communication and testing chemicals.

Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Tissue Regeneration

research Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Use in Tissue Regeneration

August 2015 in “MOJ proteomics & bioinformatics”

ePUKs could be valuable for regenerative medicine due to their wound healing abilities.

research The patch assay reconstitutes mature hair follicles by culture-expanded human cells

11 citations , July 2017 in “Regenerative Medicine”

The patch assay can create mature hair follicles from human cells and may help in hair loss treatments.

research Type II Keratins Are Phosphorylated on a Unique Motif during Stress and Mitosis in Tissues and Cultured Cells

80 citations , June 2002 in “Molecular Biology of the Cell”

Type II keratins are uniquely phosphorylated during stress and mitosis, affecting their structure and function.

research Keratinocytes-hair follicle bulge stem cells-fibroblasts co-cultures on a tri-layer skin equivalent derived from gelatin/PEG methacrylate nanofibers

11 citations , February 2020 in “Journal of Biomaterials Science Polymer Edition”

The new GelMet hydrogel can effectively support skin cell growth for tissue engineering.

research Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Use in Tissue Regeneration

August 2015 in “PubMed Central”

Epithelial-derived Pop-Up Keratinocytes (ePUKs) may enhance wound healing in regenerative medicine.

Fisetin Promotes Differentiation, Inhibits Proliferative and Inflammatory Responses in Cultured Human Cells and Alleviates Psoriasiform Dermatitis in Mice

research 713 Fisetin promotes differentiation, inhibits proliferative and inflammatory responses in cultured human cells and alleviates psoriasiform dermatitis in mice

April 2017 in “Journal of Investigative Dermatology”

Fisetin may help treat psoriasis and reduce skin inflammation.

research Autophagy is essential for maintaining the growth of a human (mini-)organ: Evidence from scalp hair follicle organ culture

42 citations , March 2018 in “PLOS Biology”

Autophagy is important for human hair growth and health.

research Considerations in the choice of a skin donor site for harvesting keratinocytes containing a high proportion of stem cells for culture in vitro

12 citations , December 2010 in “Burns”

P-auricular skin is the best donor site for high stem cell content in keratinocyte cultures.

Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia

research Induction of hair follicles using neonatal mouse dermis and human keratinocytes: relevance for improved burn wound treatments

January 2020 in “Open University of Cape Town (University of Cape Town)”

Efficient culture methods are needed to keep human keratinocytes undifferentiated for hair follicle induction.

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research Proliferation and Differentiation of Cultured Human Keratinocytes is Modulated by 1,25(OH)₂D₃ and Synthetic Vitamin D₃ Analogues in a Cell Density‐, Calcium‐ and Serum‐Dependent Manner*

research Keratinocytes maintain compartmentalization between dermal papilla and fibroblasts in 3D heterotypic tri‐cultures

research 557 Short-term Rho-associated kinase inhibitor treatment accelerates primary keratinocyte growth without affecting the characteristics of the stem cell population

research The Simplest Protocol for Rapid and Long-Term Culture of Primary Epidermal Keratinocytes from Human and Mouse

research 566 DermaCult™ Keratinocyte Expansion Medium, a Serum- and BPE-free Medium Supporting Long-term Feeder-free Expansion of Primary Human Epidermal and Pluripotent Stem Cell-Derived Keratinocytes

research Dermal papilla cells induce keratinocyte tubulogenesis in culture Elina S. ChermnykhEkaterina A. VorotelyakKsenia Y. Gnedeva • Marianna V. MoldaverYegor E. YegorovAndrey V. Vasiliev •

research Establishment and characterization of a canine keratinocyte organoid culture system

research Uptake kinetics and the effect of minoxidil on human keratinocyte cultures.

research Conditioned media obtained from human outer root sheath follicular keratinocyte culture activates signalling pathways that contribute to maintenance of hair-inducing capacity and increases trichogenicity of cultured dermal cells

research Suppression of Vitamin D Receptor and Induction of Retinoid X Receptor α Expression During Squamous Differentiation of Cultured Keratinocytes

research Human hair follicle organ culture: theory, application and perspectives

research Mesenchymal stem cells paracrine proteins from three‐dimensional dynamic culture system promoted wound healing in third‐degree burn models

research Follicular Cell Implantation: An Emerging Cell Therapy for Hair Loss

research A cell-based system for screening hair growth-promoting agents

research Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells

research Immunohistochemical detection of cytochrome P450 isoenzymes in cultured human epidermal cells.

research Use of primary keratinocyte cultures from plucked human hairs for analysis of gap junctional intercellular communication

research Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Use in Tissue Regeneration

research The patch assay reconstitutes mature hair follicles by culture-expanded human cells

research Type II Keratins Are Phosphorylated on a Unique Motif during Stress and Mitosis in Tissues and Cultured Cells

research Keratinocytes-hair follicle bulge stem cells-fibroblasts co-cultures on a tri-layer skin equivalent derived from gelatin/PEG methacrylate nanofibers

research Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Use in Tissue Regeneration

research 713 Fisetin promotes differentiation, inhibits proliferative and inflammatory responses in cultured human cells and alleviates psoriasiform dermatitis in mice

research Autophagy is essential for maintaining the growth of a human (mini-)organ: Evidence from scalp hair follicle organ culture

research Considerations in the choice of a skin donor site for harvesting keratinocytes containing a high proportion of stem cells for culture in vitro

research Prostaglandin D ₂ Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia

research The Use of Adipose-Derived Stem Cells in Selected Skin Diseases (Vitiligo, Alopecia, and Nonhealing Wounds)

research The Dermal Papilla and Hair Follicle Regeneration: Engineering Strategies to Improve Dermal Papilla Inductivity

research Accelerated senescence in skin in a murine model of radiation-induced multi-organ injury

research Induction of hair follicles using neonatal mouse dermis and human keratinocytes: relevance for improved burn wound treatments