52 citations
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February 2012 in “PloS one” Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.
51 citations
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August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
48 citations
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March 2010 in “PloS one” C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.
37 citations
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January 2010 in “Journal of Clinical Investigation” N-WASP is essential for normal hair growth in mice.
36 citations
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August 2022 in “Frontiers in Cell and Developmental Biology” Sebaceous glands age due to genetic and environmental factors, affecting sebum production and composition.
36 citations
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October 2007 in “Journal of Investigative Dermatology” Betacellulin helps blood vessel growth in wounds but delays hair growth.
35 citations
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January 2011 in “Journal of Biological Chemistry” sPLA2-X is crucial for normal hair growth and follicle health.
35 citations
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September 2009 in “Development” Necl2 affects skin cell behavior and slows wound healing.
29 citations
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January 2016 in “Experimental Dermatology” Mechanical stress may cause lesions in Hidradenitis suppurativa.
23 citations
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October 2021 in “FEBS Journal” Sonic Hedgehog helps keep skin and airway barriers healthy and reduces inflammation.
22 citations
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August 2020 in “Cells” TGM3 is important for skin and hair structure and may help diagnose cancer.
21 citations
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April 2008 in “Toxicologic Pathology” CI-1033 causes skin lesions in rats, similar to humans, due to EGF receptor inhibition.
18 citations
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October 2024 in “Medical Science Monitor” Improving skin barrier function is crucial for better acne treatment.
17 citations
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November 2001 in “Journal of Investigative Dermatology Symposium Proceedings” Stat3 is essential for hair growth and wound healing.
14 citations
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December 2018 in “The American journal of pathology” Activating Nrf2 in skin cells speeds up wound healing by increasing the growth of certain stem cells.
13 citations
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September 2022 in “Biomolecules” The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.
13 citations
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April 2019 in “iScience” EGFR helps control how hair grows and forms without needing p53 protein.
10 citations
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September 2023 in “Metabolites” Iron is crucial for skin health, with specific proteins recycling it to support skin functions and prevent its release.
10 citations
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January 2017 in “Dermato-Endocrinology” Scarring folliculitis type of acne inversa is linked to specific symptoms and lifestyle factors like smoking and being overweight.
8 citations
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July 2022 in “Biomedicines” Autophagy helps keep skin healthy and may improve treatments for skin diseases.
6 citations
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July 2021 in “Frontiers in Genetics” A gene variant causes a skin and hair disorder by disrupting protein balance.
4 citations
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April 2024 in “The Journal of Cell Biology” Caspase-1 helps hair stem cells move to heal wounded or inflamed skin.
4 citations
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December 2022 in “International Journal of Molecular Sciences” Zinc is crucial for skin health and treating various skin disorders.
3 citations
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September 2021 in “BioEssays” Dandruff might be caused by changes in how hair follicles naturally release oils and an immune response to this imbalance.
2 citations
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May 2023 in “International Journal of Molecular Sciences” The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
2 citations
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August 2019 in “Journal of skin and stem cell” The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.
2 citations
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January 2019 in “Annals of Dermatology” Melandrium firmum extract helps mice grow hair by blocking a hair loss enzyme and changing hair growth genes.
2 citations
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June 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Epigenetic factors play a crucial role in skin health and disease.
1 citations
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May 2024 in “International Journal of Molecular Sciences” Adenosine receptors could be promising targets for treating inflammatory skin diseases like psoriasis.
1 citations
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March 2024 in “International journal of molecular sciences” Radiation therapy damages skin structure and immune function, causing inflammation and potential hair loss.