research Activation of Nrf2 in keratinocytes causes chloracne (MADISH)‐like skin disease in mice
Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.
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570-600 / 1000+ resultsresearch Bone morphogenetic protein-2 (BMP-2) transactivates Dlx3 through Smad1 and Smad4: alternative mode for Dlx3 induction in mouse keratinocytes
BMP-2 activates the Dlx3 gene in mouse skin cells, important for hair and skin development.
research Directed Expression of Keratin 16 to the Progenitor Basal Cells of Transgenic Mouse Skin Delays Skin Maturation
Keratin 16 delays skin maturation and affects skin and hair development in mice.
research High proliferation and delamination during skin epidermal stratification
High proliferation and cell delamination drive early skin development, while later stages may not rely on cell division orientation.
research Modulation of the differentiated phenotype of keratinocytes of the hair follicle and from epidermis
Hair follicle cells need complex interactions to fully differentiate.
research Monoterpenoid Loliolide Regulates Hair Follicle Inductivity of Human Dermal Papilla Cells by Activating the Akt/ ¥-Catenin Signaling Pathway
Loliolide can boost hair growth by activating specific cell pathways.
research Expression patterns of programmed cell death 4 protein in normal human skin and some representative skin lesions
Increasing PDCD4 protein may help prevent or treat some skin cancers.
research Biphasic Effects of Minoxidil on the Proliferation and Differentiation of Normal Human Keratinocytes
Minoxidil affects cell growth in two ways: low doses increase growth, while high doses slow it down and can be toxic.
research FOXN1 Deficiency: from the Discovery to Novel Therapeutic Approaches
New treatments for immune disorders caused by FOXN1 deficiency are promising.
research MicroRNAs in the skin: role in development, homoeostasis and regeneration
MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
research Glycome profiling by lectin microarray reveals dynamic glycan alterations during epidermal stem cell aging
Aging changes sugar molecules on skin stem cells, which may affect their ability to repair skin.
research Fisetin Promotes Hair Growth by Augmenting TERT Expression
Fisetin, a type of polyphenol, may help hair grow by increasing certain protein activities in cells.
research Effect of minoxidil on pre- and postconfluent keratinocytes
Minoxidil prolongs cell life, slows aging, and may produce longer hairs.
research Regulation of Hair Shedding by the Type 3 IP3 Receptor
The type 3 IP3 receptor is important for controlling hair loss and growth.
research Erythropoietin promotes hair shaft growth in cultured human hair follicles and modulates hair growth in mice
Erythropoietin helps hair grow and could be a potential treatment for hair loss.
research The Notch Intracellular Domain Has an RBPj-Independent Role during Mouse Hair Follicular Development
The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.
research Roles of MED1 in Quiescence of Hair Follicle Stem Cells and Maintenance of Normal Hair Cycling
MED1 is essential for normal hair growth and maintaining hair follicle stem cells.
research In vivohair growth-stimulating effect of medicinal plant extract on BALB/c nude mice
Chrysanthemum zawadskii extract may be a better treatment for hair loss than Minoxidil.
research Suppression of Vitamin D Receptor and Induction of Retinoid X Receptor α Expression During Squamous Differentiation of Cultured Keratinocytes
As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
research The regulatory role of the tetrapeptide A cSDKP in skin and hair physiology and the prevention of ageing effects in these tissues – a potential cosmetic role
AcSDKP may help prevent skin and hair aging and promote their growth.
research Cutaneous application of α-methylspermidine activates the growth of resting hair follicles in mice
Putting α-methylspermidine on mouse skin can start hair growth.
research Impact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild‐type and BK5.AktWT mice
Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.
research Androgenetic alopecia and hair growth promotion state of the art: Present and future
Current research explores hair growth drugs, while future research aims for personalized treatments.
research Structure and Function of the Skin
The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.
research Engineered Skin Substitute Regenerates the Skin with Hair Follicle Formation
The engineered skin substitute helped grow skin with hair on mice.
research Effects of Topical application of Astragalus membranaceus in Spontaneous Alopecia Mice Model
Astragalus membranaceus helps regrow hair and reduce hair loss symptoms.
research Brassica oleracea extract, glucosinlates, and sulforaphane promote hair growth in vitro and ex vivo
Brassica oleracea extract, glucosinlates, and sulforaphane can boost hair growth and might be used to treat hair loss.
research Decay of Skin-Specific Gene Modules in Pangolins
Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.
research The role of Glucosylceramides in Keratinocyte Differentiation and Epidermal Barrier Function
Glucosylceramides are essential for healthy skin and proper wound healing.
research Structure and Function of the Skin
The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.