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Injecting lentiviral vectors into early gestation mice effectively targets skin stem cells for potential gene therapy.

HPV8 causes skin cancer by expanding specific skin stem cells.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Researchers identified key cell types and genes involved in hair and skin diseases.

Scientists found 53 keratin genes in yaks that are important for hair growth and share similarities with those in other animals.

Researchers mapped and categorized specific keratin-associated protein genes on human chromosome 21q22.1.

Some cells may slow melanoma growth, a protein could affect skin pigmentation, a gene-silencing method might treat hair defects, skin bacteria changes likely result from eczema, and a defensin protein could help treat multiple sclerosis.

New biomarkers and potential treatments for skin diseases were identified.

New and known mutations in the hairless gene cause a hair loss condition called Atrichia with papular lesions.

Overexpressing GLI-1 in mice skin can cause tumors like human basal cell carcinomas.

Skin cells can naturally limit the growth of cancerous changes by balancing cell renewal and differentiation.

Modified β-catenin causes different effects in hair and skin cells, leading to cysts or tumors.

High levels of human keratin 16 in mice cause skin lesions and abnormal skin development.

A specific gene change plus an additional mutation in the same gene cause hereditary trichilemmal cysts.

A new gene mutation causes a rare type of hair loss.

A specific gene mutation in KRT86 is linked to hair disorder in a Chinese Han family.

Overexpression of Hoxc13 in hair cells causes hair loss and skin issues.

The Bsk mutation doesn't involve keratin gene recombination and its cause is unknown.

TET enzymes are important for skin and hair development by controlling gene activity in specific areas.

PAON shows skin patterns due to genetic mosaicism.

Different keratins have unique expression patterns in mouse skin cells.

Keratinocyte gene expression is controlled by multiple modules with specific binding sites.

High levels of ODC and a mutant Ha-ras gene cause tumors in mice.

A gene mutation causes monilethrix in a Chinese family.

Keratinocytes can reverse the effects of the GNAQ oncogene, inhibiting melanoma cell growth.

A new gene location for Keratosis follicularis squamosa was found on chromosome 7p14.3-7p12.1.