research Corneodesmosomes and corneodesmosin: from the stratum corneum cohesion to the pathophysiology of genodermatoses
Corneodesmosin is crucial for skin and hair health, and its dysfunction can cause skin and hair disorders.
Search
for
Sort by
Research
150-180 / 1000+ resultsresearch Ultrastructural localization of hair keratins, high sulfur keratin-associated proteins and sulfhydryl oxidase in the human hair
Hair proteins change location and structure as hair cells mature.
research Transdifferentiation of corneal epithelium into epidermis occurs by means of a multistep process triggered by dermal developmental signals
Corneal cells can transform into skin and hair cells through specific signals.
research On the Regulation of Hair Keratin Expression: Lessons from Studies in Pilomatricomas
research 1347 Updated skin transcriptomic atlas depicted by reciprocal contribution of single-nucleus RNA sequencing and single-cell RNA sequencing
The research updated the skin cell profile, finding new skin cell markers and showing fibroblasts' key role in skin health.
research The molecular basis of human keratin disorders
research The proteomics of keratin proteins
Modern techniques have improved the understanding of keratin proteins, revealing their roles in various cells and potential in disease diagnosis.
research Mapping Human Skin: One Sequenced Cell at a Time
The article concludes that creating a detailed map of normal human skin at the single-cell level is important.
research A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity
Keratin is crucial for skin barrier formation and affects mitochondrial function.
research 567 Skin aging and carcinogenesis mechanisms by focusing on the stem cell competitive dynamics
Skin aging and cancer development are influenced by the competition between stem cells.
research Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages
Epidermal β-catenin activation changes the dermis by signaling different fibroblast types.
research Evolution of Trichocyte Keratins
Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.
research The Histology of Keratin Fibers
research Epidermal differentiation: The role of proteases and their inhibitors
Balanced protease activity is crucial for healthy skin and hair development.
research Evolution of hard proteins in the sauropsid integument in relation to the cornification of skin derivatives in amniotes
Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.
research SKPing a Hurdle: Sox2 and Adult Dermal Stem Cells
Sox2-expressing cells can help grow hair and heal skin.
research Chiton integument: Ultrastructure of the sensory hairs of Mopalia muscosa (Mollusca: Polyplacophora)
research Different keratin polypeptides in epidermis and other epithelia of human skin: a specific cytokeratin of molecular weight 46,000 in epithelia of the pilosebaceous tract and basal cell epitheliomas.
Basal-cell epitheliomas and the pilosebaceous tract share a unique keratin, distinguishing them from other skin areas.
research Epithelial barrier function: assembly and structural features of the cornified cell envelope
The cornified cell envelope forms a protective barrier in skin and hair, using specific proteins and lipids to maintain effectiveness.
research The keratins and their disorders
Mutations in keratin genes cause cell fragility and various skin disorders.
research 626 Early-stage bilayer tissue-engineered skin substitute formed by adult skin progenitor cells produces an improved skin structure in vivo
Early-stage skin substitutes improve wound healing and skin structure.
research A Niche Above: A Novel Modality of Stem Cell Regulation in Mammalian Skin Epidermis
Skin cell behavior is influenced by the tightness of nearby cells, affecting their growth and development.
research Keratin gene mutations in disorders of human skin and its appendages
Keratin gene mutations cause various skin and hair disorders, but new research offers hope for future treatments.
research The stratum corneum barrier: impaired function in relation to associated lipids and proteins
The skin's outer layer relies on lipids and proteins to protect against damage.
research The structure and organization of lanceolate mechanosensory complexes at mouse hair follicles
Lanceolate complexes in mouse hair follicles are essential for touch and depend on specific cells for maintenance and regeneration.
research The role of cathepsin E in terminal differentiation of keratinocytes
Cathepsin E is crucial for normal skin cell differentiation and development.
research Crosslinking Between Trichocyte Keratins and Keratin Associated Proteins
research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.
research A new in vitro culture system to produce a fully differentiated epidermis from human hair follicle outer root sheath cells
Researchers developed a method to grow skin-like tissue from hair cells.
research Molecular and spatial design of early skin development
The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.