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Folliculin deficiency causes problems with cell division and positioning due to disrupted RhoA signaling and interaction with p0071.

Keratin 17 is linked to various diseases, including cancer and skin conditions, and may be a target for diagnosis and treatment.

CT-707 is effective and safe for treating certain Chinese lung cancer patients.

A new mutation in the FLCN gene linked to Birt-Hogg-Dube syndrome was found, suggesting people with certain lung collapse should be tested for this mutation and screened for kidney and colon cancer.

Finasteride helps female-pattern hair loss.

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A mutant FERONIA gene affects root hair growth at high temperatures.

A KLK5 inhibitor effectively improved skin symptoms in a mouse model of Netherton Syndrome.

Finasteride helps female-pattern hair loss.

Mouse and human keratin 16 can both form filaments, with differences likely due to the tail domain, not the helical domain.

Li2CO3 improved skin disease in a mouse model of Focal Dermal Hypoplasia without toxicity.

The treatments stopped hair regrowth in mice.

Only one of the two K16 genes on chromosome 17 makes a functional protein for keratin filaments.

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Only one K16 gene on chromosome 17 makes a functional keratin protein.

A new antiandrogen compound was made and its detailed three-dimensional shape was described.

Keratin 17 is crucial for normal hair growth by regulating hair cycle transitions with TNFα.

7DHC and BM15766 damage hair follicle structure and reduce key gene expression.