35 citations
,
April 2014 in “American Journal of Medical Genetics” Boys with less severe EDA mutations in XLHED have milder symptoms and better sweat and hair production.
33 citations
,
December 2012 in “NMR in Biomedicine” Microencapsulation helps protect and track therapeutic cells, showing promise for treating various diseases, but more work is needed to improve the technology.
32 citations
,
December 2018 in “Cytokine” Type I interferons play a key role in the development of various skin diseases.
32 citations
,
June 2015 in “PLOS ONE” Olive leaf compound oleuropein helps grow hair in mice.
31 citations
,
February 2020 in “BioMed Research International” Thai people's hair density decreases with age and varies by scalp area, but hair thickness stays the same regardless of age or scalp area.
31 citations
,
July 2017 in “Clinical Science” MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
31 citations
,
February 2014 in “Inflammation Research” Lower CD200R1 on certain immune cells is linked to more severe rheumatoid arthritis and immune imbalance.
30 citations
,
June 2021 in “British Journal of Dermatology” Mutations in the WNT10A gene can cause skin, hair, teeth, and other disorders, and may also affect other areas like kidney and cancer, with potential for targeted treatments.
30 citations
,
February 2017 in “Histochemistry and Cell Biology” TPA promotes hair growth by increasing stem cell activity and activating specific cell signals.
30 citations
,
June 2016 in “Journal of Human Genetics” Researchers found genetic mutations causing hypohidrotic ectodermal dysplasia in 88% of studied patients and identified new mutations and genetic variations affecting the disease.
30 citations
,
March 2016 in “European Journal of Pharmaceutical Sciences” Optimized film improves finasteride skin absorption and treatment efficiency.
30 citations
,
June 2014 in “Seminars in Immunology” Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.
29 citations
,
December 2017 in “Molecular therapy” Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.
29 citations
,
March 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” Isoproterenol helps hair follicle stem cells turn into beating heart muscle cells.
29 citations
,
February 2007 in “Hormone and metabolic research” Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.
28 citations
,
February 2019 in “Genes” Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.
28 citations
,
November 2018 in “Journal of structural biology” Different populations have distinct hair structures related to their ancestry.
27 citations
,
March 2022 in “Forensic Toxicology” Micro-segmental hair analysis helps detect drug use patterns and estimate drug consumption days.
27 citations
,
July 2017 in “Scientific Reports” N-WASP is essential for healthy skin and preventing inflammation.
27 citations
,
April 2011 in “International journal of legal medicine” In situ DNA labeling in hair can help predict forensic DNA analysis success.
27 citations
,
August 2006 in “Laboratory Investigation” SCF and ET-1 together significantly increase skin pigmentation and melanin production.
27 citations
,
October 2001 in “Journal of Medicinal Chemistry” Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.
26 citations
,
April 2019 in “Genes” lncRNA XLOC_008679 and gene KRT35 affect cashmere fineness in goats.
26 citations
,
March 2014 in “Journal of cutaneous medicine and surgery” Topical vitamin D is useful for some skin conditions but not effective for others, and more research is needed.
26 citations
,
January 2014 in “Annals of Dermatology” Hair loss can occur when stomach cancer spreads to the scalp.
25 citations
,
February 2019 in “Genomics” Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.
25 citations
,
March 2017 in “Experimental Dermatology” The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.
25 citations
,
February 2017 in “Anticancer Research/Anticancer research” Ozone therapy might improve cancer treatment and reduce its side effects.
25 citations
,
April 2015 in “Journal of Investigative Dermatology” GasderminA3 is important for normal hair cycle transitions by controlling Wnt signaling.
25 citations
,
March 2012 in “Journal of Dermatological Science” Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.