February 2024 in “Health Sciences” Botulinum neurotoxin A is effective and safe for treating various conditions, but more clinical trials are needed to fully assess its benefits and risks.
20 citations
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January 2008 in “Journal of Korean Medical Science” NGAL may help maintain skin balance and is linked to skin disorders and cancers.
16 citations
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July 1994 in “Journal of Dermatological Science” Minoxidil sulfate and pinacidil may promote hair growth through increased blood flow, not by activating potassium channels.
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May 1988 in “Journal of Molecular Evolution” 18 citations
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July 2023 in “International Journal of Molecular Sciences” KY19382 speeds up wound healing by activating a specific cell signaling pathway.
130 citations
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April 2003 in “Journal of Investigative Dermatology” Four specific keratins in hair follicles help understand hair structure and function.
Using Arabidopsis thaliana to produce KGF-2 is a promising, cost-effective method for hair growth and wound healing products.
24 citations
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March 2016 in “Journal of Investigative Dermatology” TIP39 and PTH2R help control calcium levels and skin cell development.
19 citations
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February 2013 in “Archives of Dermatological Research” 2 citations
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May 2020 in “JAAD case reports” Ruxolitinib can cause a delayed skin reaction on the nose.
5 citations
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October 2002 in “PubMed” Human hair keratin scaffolds help repair injured muscles by breaking down and activating muscle cell growth.
1 citations
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January 2014 in “Medical Entomology and Zoology” 135 citations
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October 1997 in “Journal of biological chemistry/The Journal of biological chemistry” Trichohyalin is modified by enzymes to form strong structures in hair cells.
18 citations
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February 2015 in “Acta Crystallographica Section D: Structural Biology” The study concludes that certain domains in Clostridium histolyticum enzymes are structurally unique, bind calcium to become more stable, and play distinct roles in breaking down collagen, with potential applications in medicine and drug delivery.
54 citations
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March 2009 in “BioEssays” Hormones control keratin production in skin and hair.
44 citations
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August 1990 in “PubMed” Keratins K1 and K10 are found in the inner root sheath and cuticle of human hair follicles.
52 citations
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May 2006 in “Journal of Structural Biology” Keratin-associated proteins help link filaments and affect keratin's strength.
22 citations
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July 1998 in “Journal of Investigative Dermatology” The 4C32 gene may help in mouse skin development and differentiation.
33 citations
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January 1997 in “Journal of Investigative Dermatology” 41 citations
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May 2020 in “Frontiers in immunology” Hidradenitis suppurativa might be a type of autoinflammatory skin disease.
41 citations
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July 2020 in “Colloids and surfaces. B, Biointerfaces” Different hair protein amounts change the strength of keratin/chitosan gels, useful for making predictable tissue engineering materials.
9 citations
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July 2017 in “Journal of medical case reports” Ruxolitinib treatment may cause eyelash growth.
5 citations
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December 1996 in “Biochemical and Biophysical Research Communications” Mouse hair keratins mHa1 and mHb4 can't form a strong network on their own in cells.
28 citations
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August 1992 in “Differentiation” A new pair of mouse keratins, 65 kD and 48 kD, are found in specific skin areas and are linked to a unique skin differentiation type.
1 citations
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June 2015 in “Journal of anatomy” A compound named ZCZ90 can increase muscle spindle firing, potentially helping treat muscle spasms and hypertension.
686 citations
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February 2002 in “Current Opinion in Cell Biology” Keratin filaments are crucial for cell structure and protection, with ongoing discoveries about their genes and functions.
22 citations
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May 2011 in “Molecular Biology of the Cell” Integrin-linked kinase is crucial for normal skin healing.
110 citations
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August 2004 in “British Journal of Dermatology” The ventral matrix is the main source of the nail plate.
16 citations
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October 2022 in “Biomimetics” Trichosanthes kirilowii extract helps wounds heal faster.
66 citations
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July 2007 in “Journal of Molecular Medicine” Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.