January 1961 in “The Journal of Anthropological Society of Nippon” Hair form in mixed-blood families varies due to hereditary twist-knots and pigment formation.
Frizzy hair is fragile and can lead to hair loss and damage if not properly cared for.
May 2023 in “Accounts of chemical research” New methods can better classify curly hair types and lead to improved hair care products.
13 citations
,
November 1959 in “Annals of the New York Academy of Sciences” Genetic factors might cause fibrosing alopecia linked to hair shaft abnormalities.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” New RIPK4 gene mutations were found to cause a type of skin and limb birth defect.
Variant G of the KRTAP20-1 gene improves wool curliness in Chinese Tan sheep.
26 citations
,
February 1991 in “PubMed” Trichotillomania can be identified by a "Friar Tuck sign" and nail-biting.
30 citations
,
November 2012 in “Proceedings of the Royal Society B Biological Sciences” Hard α-keratins stay stiff in water because the surrounding matrix keeps them dehydrated and strong.
2 citations
,
July 2023 in “Urology Case Reports” Timely surgery successfully repaired a boy's penis after a hair caused severe damage.
203 citations
,
December 1947 in “Annals of Internal Medicine”
3 citations
,
January 2023 in “American journal of physiology. Cell physiology” Inward rectifier potassium channels are important in many body functions and diseases, and could be potential drug targets.
18 citations
,
January 2015 in “Experimental Dermatology” New mutations in KRT83 and KRT86 are linked to the hair disorder monilethrix.
4 citations
,
June 2014 in “The Journal of Dermatology” Elkonyxis, a rare nail condition, improved when patients stopped their nail-picking habits.
July 2022 in “Journal of Investigative Dermatology” Dkk4 is necessary for the initial development and arrangement of hair follicles.
47 citations
,
January 2017 in “RSC Advances” Keratin peptides can change hair shape gently without harsh chemicals.
October 2025 in “Journal of Neurophysiology” BK and Kv4.2 channels help Merkel cells in rat whiskers sense touch.
1 citations
,
September 2022 in “Pharmaceutics” The stiffness of a wound affects hair growth during healing, with less stiff areas growing more hair.
13 citations
,
October 2008 in “PubMed” Japanese women's curved hair has an uneven internal structure and varying amino acid composition.
1 citations
,
January 2001 in “PubMed” Mechanoreceptors convert physical touch into electrical signals through specialized nerve structures.
42 citations
,
October 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the KRT85 gene cause hair and nail problems.
11 citations
,
September 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.
Curly hair may be caused by a muscle contraction, and muscle relaxants might help treat it.
September 2023 in “Journal of the American Academy of Dermatology” Oral difelikefalin significantly reduces itch in notalgia paresthetica.
19 citations
,
December 2006 in “Journal of Structural Biology” Type I and Type II keratin chains can form heterodimers despite sequence differences.
Giant axonal neuropathy changes the structure of keratin in human hair, making it stiffer and stronger.
9 citations
,
January 2013 in “Acta dermato-venereologica” The conclusion is that "trichoknesis" should be recognized as a separate condition from trichodynia, characterized by itching instead of pain.
6 citations
,
September 2015 in “Journal of Investigative Dermatology” Using special RNA to target a mutant gene fixed hair problems in mice.
July 2019 in “Dermatologic Surgery”
9 citations
,
September 2016 in “Plastic and reconstructive surgery. Global open” The curved nonrotary punch is better for hair extraction in people with tightly curled hair.