Search

for
Search:

Sort by

Research

990-1000 / 1000+ results

research Advances in Chitosan-Based Nanoparticles for Drug Delivery

96 citations , September 2021 in “International Journal of Molecular Sciences”

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

research TCF/Lef1 activity controls establishment of diverse stem and progenitor cell compartments in mouse epidermis

91 citations , June 2011 in “The EMBO Journal”

TCF/Lef1 activity is essential for proper skin cell development and renewal.

research Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression

85 citations , January 2018 in “Cell stem cell”

Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.

research Dynamic regulation of retinoic acid-binding proteins in developing, adult and neoplastic skin reveals roles for β-catenin and Notch signalling

84 citations , September 2008 in “Developmental biology”

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

research A Missense Mutation in the Zinc-Finger Domain of the Human Hairless Gene Underlies Congenital Atrichia in a Family of Irish Travellers

83 citations , October 1998 in “The American Journal of Human Genetics”

A specific gene mutation causes complete hair loss in an Irish Traveller family.

research Mutations in the Desmoglein 4 Gene Underlie Localized Autosomal Recessive Hypotrichosis with Monilethrix Hairs and Congenital Scalp Erosions

81 citations , March 2006 in “Journal of Investigative Dermatology”

Mutations in the DSG4 gene cause specific hair and scalp issues.

research Long-term expansion and differentiation of adult murine epidermal stem cells in 3D organoid cultures

67 citations , June 2019 in “Proceedings of the National Academy of Sciences”

A new 3D culture system helps grow and study mouse skin stem cells for a long time.

research STUB1 mutations in autosomal recessive ataxias – evidence for mutation-specific clinical heterogeneity

65 citations , September 2014 in “Orphanet Journal of Rare Diseases”

Different STUB1 gene mutations cause varied symptoms in autosomal recessive ataxias.

research FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation

60 citations , July 2014 in “Autophagy”

The protein FLCN is involved in cellular cleanup and is regulated by ULK1.

research Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance

56 citations , January 2023 in “Genes & Diseases”

Repurposing existing drugs and using micronutrients may effectively target cancer stem cells and improve cancer treatment.

← Previous page