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Overexpression of PKCepsilon leads to increased TNFalpha, promoting metastatic squamous cell carcinoma in mice.

A new type of pachyonychia congenita linked to a specific keratin gene mutation was found in two Pakistani families.

A new gene mutation causes a rare type of hair loss.

Keratin 15 cells from hair follicles help develop and maintain skin tumors in mice.

A woman with a unique syndrome similar to TRPS has a genetic change near the TRPS1 gene, affecting its regulation.

Keratins are crucial for tissue strength, and mutations in keratin genes can lead to various diseases, highlighting the need for targeted therapies.

A gene mutation in mice causes skin defects and early death.

A new mutation in the ST14 gene broadens the understanding of ichthyosis-hypotrichosis syndrome.

A specific mutation in the TRPV3 gene causes hair follicle cells to develop improperly, leading to hair loss.

Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.

More research and guidelines are needed for managing prostate cancer in people with high-risk genetic mutations.

A mouse gene mutation increases the risk of skin cancer.

MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.

Dabrafenib can cause skin growths and sometimes low-grade skin cancer.

A mutation in the HR gene causes a rare form of irreversible hair loss in two Kashmiri families. Whole exome sequencing is effective for finding such mutations.

Decreasing MIG6 can increase the movement and invasiveness of MEK-inhibited mutant NRAS melanoma, particularly when stimulated by EGF.

A new mutation in the hHb1 keratin gene is linked to the hair disorder monilethrix.

A mutation in the VDR gene affects hair cycling without needing ligand binding.

A gene mutation causes lanceolate hair in rats by disrupting hair shaft integrity.

A new mutation, Glu402Lys, in hair keratin is linked to variable symptoms of monilethrix.

Overexpressing PKCepsilon in mice reduces papillomas but increases carcinomas.

Keratinocytes can reduce the survival of certain melanoma cells, suggesting new therapy paths.

A mutation in the hHb3 gene is linked to the hair disorder monilethrix.

AMPK activation may reduce melanoma risk in red-haired individuals.

Researchers found a new genetic mutation linked to a hair condition in a Japanese boy.

A new mutation in the HR gene causes hair loss in a specific family.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Using special RNA to target a mutant gene fixed hair problems in mice.

Mutations in the hHb6 gene cause the hair disorder monilethrix.