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Additional File 11 of Time-Course RNA-Seq Analysis Reveals Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Hair Follicle Growth Cycle in Capra Hircus

research Additional file 11 of Time-course RNA-seq analysis reveals stage-specific and melatonin-triggered gene expression patterns during the hair follicle growth cycle in Capra hircus

January 2022 in “Figshare”

Melatonin affects when and how certain genes work during the different stages of goat hair growth.

research The Roles of the Lrig1- and Lgr6-Positive Stem Cells in the Skin and the Functions of the Molecular Markers That Define Them

January 2014 in “eScholarship (California Digital Library)”

Lrig1 and Lgr6 stem cells help maintain hair follicles and influence skin cancer development.

research The transcription elongation factors Spt4 and Spt6 promote dermal adipocyte differentiation

March 2026 in “Adipocyte”

Spt4 and Spt6 are essential for fat cell development.

research RNase L represses hair follicle regeneration through altered innate immune signaling

February 2025 in “Journal of Clinical Investigation”

RNase L hinders hair growth by altering immune signals.

research Hereditary 1,25-Dihydroxyvitamin D Resistant Rickets due to a Mutation Causing Multiple Defects in Vitamin D Receptor Function

67 citations , August 2004 in “Endocrinology”

A specific gene mutation causes vitamin D resistance, but certain vitamin D analogs might help.

research CRISPR/Cas9-mediatedVDRknockout plays an essential role in the growth of dermal papilla cells through enhanced relative genes

2 citations , July 2019 in “PeerJ”

Removing the VDR gene in skin cells reduces their growth and affects hair-related genes.

research 5 alpha-reductase-2 gene mutations in the Dominican Republic.

53 citations , May 1996 in “The Journal of Clinical Endocrinology & Metabolism”

Different mutations in the 5 alpha-reductase-2 gene were found in affected individuals in the Dominican Republic, suggesting no common ancestry.

research AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells

17 citations , February 2019 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Alopecia Areata Totalis in a 19-Year-Old Patient with Mayer-Rokitansky-Küster-Hauser Syndrome (MRKHS)

research Alopecia areata totalis bei 19-jähriger Patientin mit Mayer-Rokitansky-Küster-Hauser-Syndrom (MRKHS)

October 2014 in “Aktuelle Dermatologie”

A 19-year-old with MRKHS developed complete hair loss, and treatment options were discussed.

research Human Epidermal Transglutaminase

53 citations , June 1983 in “Journal of Investigative Dermatology”

The enzyme is crucial for skin cell development and can be activated without proteolytic activation.

research Distinct mutations in human basic hair keratins 1 and 6 cause monilethrix: Implications for protein structure and clinical phenotype

January 1999 in “Journal of Investigative Dermatology”

Thyrotropin-Releasing Hormone Promotes Wound Re-Epithelialisation in Frog and Human Skin

research Thyrotropin-Releasing Hormone (TRH) Promotes Wound Re-Epithelialisation in Frog and Human Skin

46 citations , September 2013 in “PLOS ONE”

Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.

research Ichthyosis with confetti: clinics, molecular genetics and management

36 citations , September 2015 in “Orphanet Journal of Rare Diseases”

Revertant cell therapy could be a future treatment for Ichthyosis with confetti.

The Role of ATP-Sensitive Inward Rectifier Potassium Channels in the Regulation of Reactive Oxygen Species in the Western Honey Bee, Apis Mellifera L.

research The Role of ATP-Sensitive Inward Rectifier Potassium Channels In The Regulation of Reactive Oxygen Species In The Western Honey Bee, APIS Mellifera L.

June 2022

Activating certain potassium channels in honey bees can lower antioxidant levels and reduce death rates during heavy mite infestations, potentially aiding their immune response.

research Hard Keratin IF and Associated Proteins

22 citations , January 1990

research EGFR: stopping stathmin to start the cycle

March 2016 in “Experimental Dermatology”

EGFR helps hair follicles transition properly by controlling Stathmin levels.

research Ligand‐independent Regulation of the hairless Promoter by Vitamin D Receptor^†

10 citations , February 2008 in “Photochemistry and photobiology”

Vitamin D receptor can control the hairless gene linked to hair loss even without vitamin D.

research Novel insights into cardiocutaneous syndromes

May 2022

Understanding genetics is crucial for treating heart and skin diseases.

research A homozygous missense mutation in the fibroblast growth factor 5 gene is associated with the long-hair trait in Angora rabbits

5 citations , June 2023 in “BMC genomics”

A specific gene mutation causes long hair in Angora rabbits.

research GATA3 inhibits proliferation and induces expression of both early and late differentiation markers in keratinocytes of the human epidermis

24 citations , December 2013 in “Archives of Dermatological Research”

research Case report: Heterozygous mutation in HTRA1 causing typical cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy

1 citations , September 2023 in “Frontiers in Genetics”

A heterozygous mutation in HTRA1 can cause severe CARASIL symptoms.

research Significance of stress keratin expression in normal and diseased epithelia

47 citations , January 2024 in “iScience”

Stress keratins are expressed less in diseased skin and are linked to differentiation, inflammation, and immunity.

research Pre-keratin isolated from epidermal microsomes

7 citations , December 1970 in “Biochimica et Biophysica Acta (BBA) - Protein Structure”

research Delayed Wound Healing in Keratin 6a Knockout Mice

149 citations , July 2000 in “Molecular and Cellular Biology”

Keratin 6a is important for quick wound healing from hair follicles.

research Investigations into the roles of potassium channels in hair growth : studies confirming the presence of several ATP-sensitive potassium (K+ATP) channels in hair follicles and exploring their mechanism of action using molecular biological, cell culture, organ culture and proteomic approaches

November 2010 in “Bradford Scholars (University of Bradford)”

KATP channels are crucial for hair growth, and targeting them may lead to new hair loss treatments.

research Differential Expression of Genes Encoding a Cysteine-Rich Keratin Family in the Hair Cuticle

35 citations , September 1994 in “Journal of Investigative Dermatology”

research [An immunohistochemical study on the normal human skin using an anti-hair keratin monoclonal antibody (HKN-2)].

February 1985 in “PubMed”

research Polymorphism of keratin-associated protein (KAP) 7 gene and its association with wool traits in Rambouillet sheep

3 citations , May 2018 in “The Indian Journal of Animal Sciences”

The KAP 7 gene affects wool traits in Rambouillet sheep, with the BB genotype showing the best wool characteristics.

research Alopecia in a Novel Mouse Model RCO3 Is Caused by mK6irs1 Deficiency

42 citations , September 2003 in “Journal of Investigative Dermatology”

A missing mK6irs1 gene causes hair loss in mice.

research The IRE gene encodes a protein kinase homologue and modulates root hair growth in Arabidopsis

66 citations , May 2002 in “The Plant Journal”

The IRE gene is important for normal root hair growth in Arabidopsis plants.

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