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research Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression

85 citations , January 2018 in “Cell stem cell”

Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.

research Dermal Blimp1 Acts Downstream of Epidermal TGFβ and Wnt/β-Catenin to Regulate Hair Follicle Formation and Growth

85 citations , June 2017 in “Journal of Investigative Dermatology”

Blimp1 is crucial for hair follicle growth and skin health.

research The molecular basis of human keratin disorders

79 citations , February 2009 in “Human Genetics”

research Loss-of-Function Mutations in HOXC13 Cause Pure Hair and Nail Ectodermal Dysplasia

74 citations , October 2012 in “The American Journal of Human Genetics”

Mutations in the HOXC13 gene cause hair and nail development issues.

research The disruption of Sox21-mediated hair shaft cuticle differentiation causes cyclic alopecia in mice

73 citations , May 2009 in “Proceedings of the National Academy of Sciences”

Disrupting the Sox21 gene in mice causes hair loss and regrowth cycles.

research Genomic Organization, Transcriptomic Analysis, and Functional Characterization of Avian α- and β-Keratins in Diverse Feather Forms

72 citations , August 2014 in “Genome Biology and Evolution”

Feather diversity is due to different keratin gene combinations, and chickens can help study human keratin diseases.

research Novel Type I Hair Keratins K39 and K40 Are the Last to be Expressed in Differentiation of the Hair: Completion of the Human Hair Keratin Catalog

70 citations , February 2007 in “Journal of Investigative Dermatology”

K39 and K40 are the last keratins expressed in hair development, completing the hair keratin catalog.

research Long-term expansion and differentiation of adult murine epidermal stem cells in 3D organoid cultures

67 citations , June 2019 in “Proceedings of the National Academy of Sciences”

A new 3D culture system helps grow and study mouse skin stem cells for a long time.

research Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis

65 citations , November 2013 in “The EMBO Journal”

HDAC1 is crucial for skin development and preventing tumors.

research Human Induced Pluripotent Stem Cell–Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo

64 citations , January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology”

Human stem cells can help form hair follicles in mice.

research Deimination and Peptidylarginine Deiminases in Skin Physiology and Diseases

57 citations , January 2020 in “International Journal of Molecular Sciences”

PADs are crucial for healthy skin and hair, and their imbalance can cause skin and hair disorders.

research Macrophages in Skin Wounds: Functions and Therapeutic Potential

56 citations , November 2022 in “Biomolecules”

Targeting macrophages may improve wound healing.

research Endogenous Retinoids in the Pathogenesis of Alopecia Areata

54 citations , September 2012 in “The journal of investigative dermatology/Journal of investigative dermatology”

Vitamin A affects hair loss and immune response in alopecia areata.

research Human Hair and the Impact of Cosmetic Procedures: A Review on Cleansing and Shape-Modulating Cosmetics

53 citations , July 2016 in “Cosmetics”

Future hair cosmetics will be safer and more effective.

research The roles of activins in repair processes of the skin and the brain

52 citations , July 2001 in “Molecular and cellular endocrinology”

Activin A helps heal skin wounds and protects the brain after injury.

research S100A6: molecular function and biomarker role

50 citations , September 2023 in “Biomarker Research”

S100A6 is important for cell functions and can help diagnose and treat diseases.

research Integrative analysis reveals ncRNA-mediated molecular regulatory network driving secondary hair follicle regression in cashmere goats

50 citations , March 2018 in “BMC Genomics”

Non-coding RNAs help control hair growth cycles in cashmere goats, suggesting ways to improve cashmere production.

research Alopecia areata: What’s new in the epidemiology, comorbidities, and pathogenesis?

49 citations , October 2023 in “Journal of Dermatological Science”

research Integrated single-cell chromatin and transcriptomic analyses of human scalp identify gene-regulatory programs and critical cell types for hair and skin diseases

47 citations , July 2023 in “Nature Genetics”

research Severe Skin Permeability Barrier Dysfunction in Knockout Mice Deficient in a Fatty Acid ω-Hydroxylase Crucial to Acylceramide Production

40 citations , July 2019 in “Journal of Investigative Dermatology”

Lack of a key enzyme causes severe skin issues and death in mice.

research Structural Stability of Wild Type and Mutated α-Keratin Fragments: Molecular Dynamics and Free Energy Calculations

40 citations , September 2004 in “Biomacromolecules”

The Glu413Lys mutation in keratin affects hair stability, while Glu413Asp does not.

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