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NKIRAS2 can suppress certain skin tumors but its effect on cancer varies with context and expression level.

Researchers made a mouse model with curly hair and hair loss by editing a gene.

KRTAP10 proteins help form the hair shaft's tough outer layer by interacting with specific hair keratins.

Keratins K6 and K16 are expressed more freely in regenerating mouse skin than K1 and K10.

K6 gene expression can be controlled and manipulated in mice for studying skin disorders.

Different hair types in mammals are linked to variations in specific protein genes, with changes influenced by their living environments.

SETDB1 is essential for controlling DNA methylation, silencing retrotransposons, and maintaining skin cell health, with its absence leading to skin inflammation and hair loss.

Keratin 6A increases skin inflammation, suggesting it could be a target for treating certain skin diseases.

K31 can identify clear secretory cells in human sweat glands.

A KLK5 inhibitor effectively improved skin symptoms in a mouse model of Netherton Syndrome.

The KRTAP11-1 gene promoter is crucial for specific expression in sheep wool cortex.

A chimeric keratin partially improved skin structure in mice lacking keratin 5, but didn't fully restore normal skin.

Normal cells outcompete and remove mutant cells in the pancreas with the help of the EphA2 receptor.

CXCR2 in skin cells promotes tumor growth.

A specific genetic change in the KRT71 gene causes a hair loss condition in Hereford cattle.

Deleting the CD271 gene in mouse skin cells leads to disorganized skin and increased hair growth, suggesting CD271 is important for skin health.

KRTAP genes evolved early in mammals, leading to diverse hair traits.

Different versions of the KRTAP6-2 gene in goats can lead to thinner cashmere fibers.

ATP-sensitive potassium channels are important for hair growth.

LRIG1 protein affects hair growth by regulating skin receptors, leading to hair loss when overexpressed.

Specific gene variants affect wool traits in Chinese Tan sheep.

lncRNA2919 slows down rabbit hair growth by stopping cell growth and causing cell death.

Krox20 (Egr2) is important for the function of epithelial stem cells.

Keratin 79 cells help form and regenerate hair canals.

Human hair keratin genes have unique simple sequence repeats that may help track genetic variations.

The study found that variations in hair protein genes are likely due to evolutionary deletions or duplications.

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

Certain gene variations are linked to the thickness of cashmere goat hair.