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The TRPV3 channel structure changes linked to severe itch and hyperkeratosis were identified using cryo-EM.

The ABI1 gene contributes to prostate cancer progression and treatment resistance.

SPT6 prevents excessive skin inflammation by blocking a feedback loop.

Interleukin-1 increases keratin K6 production in skin cells.

Keratin is crucial for skin barrier formation and affects mitochondrial function.

Type II keratins are uniquely phosphorylated during stress and mitosis, affecting their structure and function.

Mouse keratin 6 isoforms have different expression patterns in various tissues.

Acid can block TRPV3 from outside the cell but boost its function from inside.

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.

Nonimmunogenic forms of keratins K71 and K31 can delay and prevent alopecia areata.

ITK inhibitors may effectively treat alopecia areata.

Increasing type 17 collagen reduces aging signs in skin cells caused by UV light.

Hair germ cells differ from epidermal cells in keratin expression, and specific keratins form after hair differentiation.

Matriptase is crucial for skin, hair, and immune cell health, and its imbalance can lead to cancer.

K6 gene expression can be controlled and manipulated in mice for studying skin disorders.

Caspase-14 is important for skin and hair development in all mammals.

ZPK helps skin cells mature and may affect skin health.

K14 expression in young rats differs from adults.

AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.

A specific DNA region controls skin cell gene expression by working with certain proteins.

Short-term treatment with ROCKi increases skin cell growth without changing stem cell features.

Mice with human-like EGFR had growth issues, skin defects, heart problems, and unusual bone development.

Rabbits with Sarcoptes scabiei had thicker skin, cell death, and skin hardening.

The enzyme Dgat1 is essential for healthy hair and skin by controlling retinoid levels.