20 citations
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January 2000 in “Dermatologic Clinics” New psoriasis treatments are effective but come with side effects and risks.
17 citations
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September 2014 in “PLoS ONE” SK2 channels help control sensory signals in rat muscle spindles and hair follicles.
12 citations
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March 2017 in “Medicinal Chemistry Research” Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.
12 citations
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November 2014 in “PLOS Computational Biology” The study concluded that hair growth in mice is regulated by a stable interaction between skin cell types, and disrupting this can cause hair loss.
8 citations
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May 2021 in “Bioengineering & translational medicine” Hair growth environment recreated with challenges; stem cells make successful skin organoids.
7 citations
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February 2015 in “Journal of comparative pathology” CD8+ T cells play a key role in graft-versus-host disease in certain mice models.
5 citations
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April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Aging skin shows thinner layers, fewer hair follicles, and new biomarkers like increased space between cells and smaller sebaceous glands.
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October 2022 in “Frontiers in public health” Cadmium chloride pollution can cause skin disorders, speed up aging, and prevent hair growth.
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September 2005 in “Experimental dermatology” The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.
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January 2016 in “Elsevier eBooks” The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.
Ca²⁺-mediated protein citrullination controls cell growth in the CNS and may help treat brain tumors.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Adipocytes can change into fibroblast-like cells to help with wound healing.
September 2022 in “Institutional Repositories DataBase (IRDB)” 3D-oxy exosomes may significantly boost hair growth, offering new treatment options for hair loss.
January 2018 in “Elsevier eBooks” Topical imiquimod is as effective as 5-fluorouracil for treating actinic keratosis, with about a 5% risk of it turning into squamous cell carcinoma.
April 2017 in “Journal of Investigative Dermatology” Chemotherapy and radiation therapy cause skin and hair damage by altering gene expression and signaling pathways.
April 2015 in “Andrology” HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.
314 citations
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April 2010 in “Developmental Cell” β-catenin in the dermal papilla is crucial for normal hair growth and repair.
64 citations
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August 2013 in “Mayo Clinic Proceedings” Wound healing insights can improve regenerative medicine.
59 citations
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October 2020 in “Stem Cell Reviews and Reports” Men have higher COVID-19 mortality rates than women due to biological and lifestyle factors.
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June 2023 in “Nature Aging” Blocking IL-17 signaling may reduce skin inflammation and delay aging.
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January 2020 in “Ecology and evolution” Genes related to pigmentation, body rhythms, and behavior change during hares' seasonal coat color transition, with a common genetic mechanism in two hare species.
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March 2013 in “International Journal of Cosmetic Science” AcSDKP may help prevent skin and hair aging and promote their growth.
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August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.
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June 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
277 citations
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July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
260 citations
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December 2012 in “Cold Spring Harbor Perspectives in Biology” Wnt signaling is crucial for skin development and health, and its disruption can cause skin diseases.
224 citations
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March 2006 in “Seminars in Cutaneous Medicine and Surgery” The document concludes that understanding hair follicle biology can lead to better hair loss treatments.
205 citations
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March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
150 citations
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October 2010 in “The American Journal of Pathology” The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
146 citations
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May 2002 in “The American journal of pathology” Cathepsin L is essential for normal hair growth and development.