research De novo assembly and annotation of Asiatic lion (Panthera leo persica) genome
The Asiatic lion has very low genetic diversity and unique genetic traits, highlighting the need for its conservation.
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research A Rare Case of Acrodermatitis Enteropathica in a One Year Old Child
A one-year-old child with a genetic condition had symptoms improved by treating zinc deficiency.
research Synthesis, antiproliferative, acute toxicity and assessment of antiandrogenic activities of some newly synthesized steroidal lactams
research Side-Effects of Spironolactone Therapy in the Hirsute Woman
Spironolactone can cause side effects like irregular bleeding, but lower doses may reduce these effects and still improve hirsutism.
research Spironolactone is an Effective and Well Tolerated Systemic Antiandrogen Therapy for Hirsute Women*
Spironolactone effectively reduces hair growth in women with hirsutism and is generally well-tolerated.
research Medical treatment of hirsutism
The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.
research Lights triggered differential accumulation of antioxidant and antidiabetic secondary metabolites in callus culture of Eclipta alba L.
Red light boosts beneficial compounds in Eclipta alba cultures.
research Hypotensive Activity and Toxicology of Constituents from Bombax ceiba Stem Bark.
Bombax ceiba stem bark extracts can lower blood pressure, but high doses can be toxic and lethal.
research A prospective, randomized trial comparing flutamide (250 mg/d) and finasteride (5 mg/d) in the treatment of hirsutism
Flutamide reduces hair growth better but has more side effects.
research Androgens Affect the Activity of Human Sebocytes in Culture in a Manner Dependent on the Localization of the Sebaceous Glands and Their Effect Is Antagonized by Spironolactone
Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.
research Successful treatment of female-pattern hair loss with spironolactone in a 9-year-old girl
Spironolactone successfully treated hair loss in a 9-year-old girl.
research A comparison between finasteride, flutamide, and finasteride plus flutamide combination in the treatment of hirsutism
Flutamide works better than finasteride for hirsutism, and combining both is slightly better but not much.
research Efficacy of platelet-rich plasma in androgenetic alopecia patients
PRP therapy safely improves hair growth in people with hair loss.
research Application of Different Analytical Techniques and Microbiological Assays for the Analysis of Macrolide Antibiotics from Pharmaceutical Dosage Forms and Biological Matrices
Future work on macrolide antibiotic analysis will aim to enhance selectivity, sensitivity, and efficiency using advanced chromatographic methods.
research Spironolactone in dermatology: uses in acne and beyond
Spironolactone is a low-cost, effective, and generally safe treatment for various skin conditions related to hormones.
research Treatment of hyperandrogenism in women
Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.
research Pantolactams as androgen receptor antagonists for the topical suppression of sebum production
Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.
research Efficacy and Safety of Spironolactone in Acne Management
Spironolactone is effective and safe for treating acne.
research MARKETING ANALYSIS OF SUPPLYING THE PHARMACEUTICAL MARKET WITH DRUGS BASED ON BURCH (ARCTIUM LAPPA L.)
Burdock has potential for new pharmaceutical products due to its medicinal properties.
research Miscellaneous Steroids
The document concludes that scientists created various steroids with different properties, including a more effective semi-synthetic vitamin D.
research Allergic contact dermatitis produced by canrenone
A woman had an allergic skin reaction to a hair loss treatment containing canrenone.
research Journal Watch
A test for nail fungus was most accurate with PAS stain, low-dose spironolactone helped two-thirds of acne patients, metformin reduced symptoms of HIV-related fat distribution changes with some side effects, and skin examination with dermoscopy was better at detecting abnormal moles, while temporary tattoos can cause skin reactions.
research Functional lacrimal gland regeneration by transplantation of a bioengineered organ germ
Bioengineered lacrimal glands can restore tear production and protect eyes.
research Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression
Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.
research Androgen excess is the key element in polycystic ovary syndrome
Too much male hormone is the main cause of Polycystic Ovary Syndrome.
research Topical minoxidil in the treatment of alopecia areata.
Minoxidil helps hair regrowth in alopecia patients, with 16 having good results and no side effects.
research Female Gonadal Function before and after Treatment of Acromegaly
Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.
research Efficacy of myo-inositol in the treatment of cutaneous disorders in young women with polycystic ovary syndrome
Myo-inositol helps improve skin conditions and metabolic profiles in young women with PCOS.
research What may be the markers of the male equivalent of polycystic ovary syndrome?
Some men with early hair loss may have a condition similar to PCOS in women.
research Current evaluation of amenorrhea
The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.