research LB881 Unraveling mechanisms of scarring alopecia in discoid lupus: Insights from spatial transcriptomics
CD8+ T cells attack hair follicle stem cells, causing scarring and hair loss in Discoid Lupus.
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180-210 / 1000+ resultsresearch Co-factors of LIM domains (Clims/Ldb/Nli) regulate corneal homeostasis and maintenance of hair follicle stem cells
Clim proteins are essential for maintaining healthy corneas and hair follicles.
research 178 Neutrophil elastase is critical in linear IgA bullous dermatosis in mice
CD8+ T cells attack hair follicle stem cells, causing scarring and hair loss.
research Growth and differentiation of human keratinocytes cultured on eye lens capsules
Eye lens capsules are the best for growing human skin cells.
research Microscopy‐guided laser ablation for the creation of complex skin models with folliculoid appendages
Researchers used a laser to create advanced skin models with hair-like structures.
research 555 Dermal single-cell atlas: a novel tool to explore fibroblast heterogeneity
A new tool helps study hair follicle cells to develop better treatments for hair disorders.
research Defining compartmentalized stem and progenitor populations with distinct cell division frequency in the ocular surface epithelium
Stem and progenitor cells in the eye have different division rates and locations, affecting how they respond to injury.
research Lamins in development, tissue maintenance and stress
Lamins are vital for cell survival, organ development, and preventing premature aging.
research Distinct Fibroblast Lineages Give Rise to NG2+ Pericyte Populations in Mouse Skin Development and Repair
Ng2+ perivascular cells in mouse skin come from specific fibroblast types and help in tissue repair.
research Live Imaging of the Skin Immune Responses
Live imaging helps us understand skin immune responses and develop treatments.
research Skinny Fat Cells Stimulate Wound Healing
Skinny fat cells help wounds heal faster by releasing fatty acids.
research “Dark Cells” in Normal, Hyperplastic, and Promoter-Treated Mouse Epidermis Studied by Conventional and High-Voltage Electron Microscopy
research Long-term live imaging, cell identification and cell tracking in regenerating crustacean legs
A new method allows detailed tracking of cell regeneration in crustacean legs.
research Hair-follicle-associated pluripotent (HAP) stem cells
HAP stem cells can repair nerves and spinal cords by becoming Schwann cells.
research Homeostatic maintenance of the murine corneal epithelium in pathophysiological contexts
Corneal health relies on cell migration and cooperation with the lacrimal gland, not Bmi1+ cells, and Eda gene mutations can cause dry eye disease.
research The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling
Cathepsin L is essential for normal hair growth and development.
research Avaliação do perfil fenotípico, proliferativo e secretório de células-tronco mesenquimais do tecido adiposo captadas por lipoaspiração assistida por laser
Mesenchymal stem cells from laser-assisted liposuction are as effective and safe as those from conventional methods for cell therapy.
research A Fluorescence-based Lymphocyte Assay Suitable for High-throughput Screening of Small Molecules
The assay effectively identifies compounds that affect immune cell activation.
research CD4 T cells from mice with alopecia areata express an effector like phenotype and can transfer disease
CD4 T cells can cause alopecia areata by activating CD8 T cells to attack hair follicles.
research Maintenance of Barrier Tissue Integrity by Unconventional Lymphocytes
Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.
research Generating detailed intercellular communication patterns in psoriasis at the single-cell level using social networking, pattern recognition, and manifold learning methods to optimize treatment strategies
New insights into cell communication in psoriasis suggest innovative drug treatments.
research Editors’ Picks
A specific type of immune cell plays a key role in causing alopecia areata and could be a target for treatment.
research Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis
Deleting a specific protein in skin cells disrupts normal hair growth and development.
research Human Dermal Fibroblasts Demonstrate Positive Immunostaining for Neuron- and Glia- Specific Proteins
Fibroblasts can be mistaken for neural cells, so functional validation is needed.
research M-CSF-stimulated myeloid cells can convert into epithelial cells to participate in re-epithelialization and hair follicle regeneration during skin wound healing
Myeloid cells can turn into skin and hair cells to help heal wounds.
research Impaired Hair Follicle Morphogenesis and Cycling with Abnormal Epidermal Differentiation in nackt Mice, a Cathepsin L-Deficient Mutation
Cathepsin L deficiency causes hair and skin issues in mice.
research CD49fhigh Defines a Distinct Skin Mesenchymal Stem Cell Population Capable of Hair Follicle Epithelial Cell Maintenance
A specific group of skin stem cells was found to help maintain hair follicle cells.
research Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin
Hair follicles help attract immune cells to the skin during stress.
research 1397 LSD1 is critical for epidermal development and skin barrier formation
LSD1 is essential for healthy skin development and creating the skin's protective barrier.
research Telocytes in human skin – are they involved in skin regeneration?
Telocytes might help with skin repair and regeneration.