4 citations
,
November 2021 in “Journal of Clinical Medicine” Higher levels of CCL7 are linked to more severe hair loss in alopecia areata patients.
7 citations
,
May 2005 in “Experimental Dermatology” Two mouse mutations cause similar hair loss despite different skin changes.
2 citations
,
July 2016 in “Veterinary dermatology” Hyperaesthetic leucotrichia in horses causes painful, recurring skin lesions and hair color changes, especially in Arabian and American paint horses.
1 citations
,
October 2000 in “Journal of Investigative Dermatology” The Thr1022Ala variant in the hairless gene is not a disease-causing mutation.
88 citations
,
March 2004 in “Journal of Investigative Dermatology” September 2020 in “Benha Journal of Applied Sciences” Higher IL-19 levels are linked to more severe Alopecia Areata.
April 2023 in “Journal of Investigative Dermatology” An elderly woman's upper lip lump, thought to be a mucocele, was actually a rare type of lymphoma usually found on legs, treated successfully with chemotherapy and radiation.
August 2023 in “Sabuncuoglu Serefeddin Health Sciences” CT60 polymorphism might increase the risk of Alopecia Areata.
5 citations
,
February 2024 in “Journal of Investigative Dermatology” Alopecia areata patients have fewer protective regulatory B cells, which may contribute to the disease.
14 citations
,
January 1990 in “Fertility and Sterility” Some patients with high prolactin levels don't show symptoms because they have a form of the hormone that's less active.
Donor lymphocyte infusions effectively treated leukemia relapse but caused vitiligo and alopecia areata.
March 2021 in “Annals of Translational Medicine” Two patients with lupus had an unusual type of hair loss not typical for the disease.
10 citations
,
June 2001 in “Annals of neurology” Alzheimer's patients have higher levels of certain chemicals in their hair.
2 citations
,
January 2018 Diffuse alopecia areata causes widespread hair thinning due to an autoimmune response.
6 citations
,
October 2021 in “Biomedical Research and Therapy” Alopecia areata patients have higher levels of IL-6 and TNF-α.
April 2011 in “Medical Journal of Tabriz University of Medical Sciences and Health Services” Many patients with Alopecia Areata have underlying autoimmune disorders, especially thyroid issues.
3 citations
,
September 2022 in “European Journal of Dermatology”
19 citations
,
January 2001 in “Internal Medicine” Protein-losing enteropathy worsened with lupus symptoms but improved with prednisolone.
4 citations
,
March 2002 in “International journal of toxicology” LAAM caused developmental toxicity in tolerant rats without causing birth defects.
15 citations
,
June 2012 in “British Journal of Dermatology” A new mutation in the KRT86 gene causes a hair disorder with variable expression.
7 citations
,
January 2012 in “International Journal of Trichology” Sudden, unusual hair loss may indicate serious underlying health issues.
8 citations
,
December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Mouse models help understand alopecia areata and find treatments.
2 citations
,
January 2020 in “Enlighten: Theses (The University of Glasgow)” Alopecia areata is an autoimmune disease causing hair loss, and targeting macrophages may help treat it.
June 2020 in “Jurnal Penyakit Dalam Indonesia” Anti-DFS70 antibodies can help identify nonsystemic autoimmune conditions in SLE patients.
3 citations
,
January 2003 in “Cell Structure and Function” Injecting certain cells into mice caused hair loss, which was preventable with a specific inhibitor.
176 citations
,
August 2015 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.
36 citations
,
July 2007 in “Journal of Investigative Dermatology” Certain HLA class II alleles increase or decrease the risk of alopecia areata.
September 2024 in “Journal of the American Academy of Dermatology” The patient responded well to treatment with no disease progression.
October 2024 in “GE Portuguese Journal of Gastroenterology” Unexplained excessive hair growth can signal underlying cancer and often indicates a poor prognosis.
April 2023 in “Journal of Investigative Dermatology” IL-17 plays a key role in severe hair loss in chronic alopecia areata.