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January 1981 in “Cells Tissues Organs” Human hair cuticle has five cell layers with specific junctions and granules.
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July 2015 in “PLoS ONE” The study revealed the detailed structure of a keratin dimer, aiding understanding of how intermediate filament proteins function.
186 citations
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December 2012 in “Current opinion in cell biology” Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.
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August 2004 in “British Journal of Dermatology” The ventral matrix is the main source of the nail plate.
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October 2022 in “Bioengineering” Keratin helps skin cells mature when added to a collagen mix, which could be important for skin and hair health.
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December 1986 in “The journal of cell biology/The Journal of cell biology” Hair and nail cells share similar proteins, indicating a common differentiation pathway.
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January 2013 in “Biomaterials” Keratin from human hair shows promise for medical uses like wound healing and tissue engineering.
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January 2003 in “Plastic & Reconstructive Surgery” Nail-matrical fibroblasts can make non-nail cells produce hard keratin, useful for nail repair.
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August 1981 in “PubMed” Trichilemmal keratinization is a unique process in hair follicles where the outer root sheath turns into keratin without a specific layer.