138 citations
,
June 2019 in “Stem Cells and Development” Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.
5 citations
,
November 2005 Confocal Laser Scanning Microscopy is effective for tracking compounds in the skin.
28 citations
,
June 2023 in “Tissue Engineering and Regenerative Medicine” Non-immune dermal cells dominate, epidermal cells increase after day 9, and certain immune cells persist beyond inflammation in wound-induced hair follicle regeneration.
173 citations
,
January 2014 in “Nature Cell Biology” Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.
January 2018 in “Stem cell biology and regenerative medicine” The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.
24 citations
,
July 2015 in “Molecular Medicine Reports” Lysophosphatidic acid boosts stem cell growth and movement by creating reactive oxygen species.
December 2022 in “Frontiers in plant science” CCDC22 and CCDC93 are essential for root and root hair growth in Arabidopsis.
31 citations
,
September 2016 in “PLoS ONE” Cell division orientation varies by body site and is linked to epidermal thickness and cell density.
84 citations
,
October 2007 in “The Journal of Immunology” Myeloid-derived suppressor cells help control autoimmune cells and promote hair regrowth in alopecia areata.
August 2023 in “Journal of Investigative Dermatology” Skin organoids can regenerate hair by forming specific cell units with certain signals.
Dermal papilla cells can help form hair-like structures in lab-grown skin cells.
2 citations
,
May 2024 in “Immunity” Stem cells help control the immune response to improve wound healing.
52 citations
,
October 2005 in “Journal of Investigative Dermatology” Hair follicle stem cells have greater longevity and adhesion, while transit-amplifying cells are more mobile.
July 2025 in “Journal of Investigative Dermatology” Ritlecitinib reduces alopecia areata symptoms by blocking JAK3/TEC signaling and T-cell activity.
July 2025 in “Journal of Investigative Dermatology” Schwann cell and M2 macrophage interactions contribute to keloid growth by increasing matrix deposition.
6 citations
,
September 2019 in “Skin pharmacology and physiology” RCS-01 therapy is safe and may improve skin structure by affecting gene expression.
January 2006 in “中华医学杂志:英文版” Cultured skin cells can trigger hair growth and the amount of certain proteins they produce affects their ability to regenerate hair follicles.
6 citations
,
June 2024 in “Biofabrication” A small 3D skin model helps study how immune cells move in the skin.
Scientists improved how to grow mouse skin cells in the lab and created a long-lasting cell line, but didn't fully explain its advantages or compare it to normal cells.
721 citations
,
October 2011 in “Nature” Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.
25 citations
,
December 1992 in “Seminars in cell biology” Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
April 2023 in “Dermatology practical & conceptual” Lenalidomide helps hair follicle stem cells turn into melanocytes, which may improve repigmentation in vitiligo.
September 2016 in “Journal of Dermatological Science” The protein aPKCλ is crucial for keeping hair follicle stem cells inactive and for hair growth and regeneration.
60 citations
,
September 2023 in “Science” BTNL proteins help control inflammatory bowel disease by maintaining specific immune cells.
19 citations
,
January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology” A special environment is needed to fully activate sleeping stem cells.
6 citations
,
November 2023 in “JCI Insight” Exogenous stem cells can effectively integrate into hair follicles, promoting hair growth.
January 2024 in “Biomaterials Research” The new 3D system helps test hair growth treatments effectively.
236 citations
,
April 2015 in “Cell” Plucking some hairs can trigger nearby unplucked hairs to grow back more due to a collective response.
88 citations
,
January 2019 in “Journal of Tissue Engineering and Regenerative Medicine” Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.