research Gonadal dysgenesis and bone metabolism
Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.
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research Oxidative Activity of the Type 2 Isozyme of 17β-Hydroxysteroid Dehydrogenase (17β-HSD) Predominates in Human Sebaceous Glands
The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.
research Identification of hair shaft progenitors that create a niche for hair pigmentation
Scientists found cells in hair that are key for growth and color.
research Current Status of Fractional Laser Resurfacing
Fractional laser resurfacing is effective and safe for skin treatment, with benefits like less downtime and a low risk of adverse events.
research Roles of tumor suppressors in regulating tumor-associated inflammation
Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.
research Chemotherapy-induced alopecia
Many patients find hair loss from chemotherapy very distressing, and while treatments like minoxidil and scalp cooling may help, there is no sure way to prevent it.
research Tumor Mapping in 2 Large Multigenerational Families With CYLD Mutations
CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.
research Estrogens and Human Scalp Hair Growth—Still More Questions than Answers
The effects of estrogen on human hair growth are unclear and need more research.
research Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne
Genetic variations affecting skin structure play a key role in severe acne.
research Low-level laser treatment accelerated hair regrowth in a rat model of chemotherapy-induced alopecia (CIA)
Low-level laser treatment helped rats regrow hair faster after chemotherapy.
research Investigation of human hair fibers using lateral force microscopy
Hair treatments like bleaching increase friction by exposing tiny pores on the hair surface.
research Drug repositioning: current approaches and their implications in the precision medicine era
Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.
research Transient mitochondrial DNA double strand breaks in mice cause accelerated aging phenotypes in a ROS-dependent but p53/p21-independent manner
Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.
research Dermal nanocrystals from medium soluble actives – Physical stability and stability affecting parameters
Caffeine nanocrystals for skin products stay stable with the right stabilizer, but grow in size at higher temperatures.
research Recent positive selection of a human androgen receptor/ectodysplasin A2 receptor haplotype and its relationship to male pattern baldness
A specific genetic mutation may increase male pattern baldness risk, especially in Europeans.
research A wearable and stretchable dual-wavelength LED device for home care of chronic infected wounds
A new wearable LED device helps heal chronic infected wounds at home.
research Tobacco and the skin
Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.
research A splice variant in KRT71 is associated with curly coat phenotype of Selkirk Rex cats
A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.
research Loose anagen hair syndrome
Loose Anagen Syndrome is a hair condition where hairs can be easily pulled out, mainly affecting young girls, and may improve on its own or with treatment.
research Drug Repurposing - Hypothesis, Molecular Aspects and Therapeutic Applications
Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
research Asian Hair: A Review of Structures, Properties, and Distinctive Disorders
Asian hair is generally straight and thick, with unique disorders and properties, and more research is needed to understand it fully.
research Design of a RADA16-based self-assembling peptide nanofiber scaffold for biomedical applications
RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.
research Hair loss and herbs for treatment
Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.
research Topical Melatonin for Treatment of Androgenetic Alopecia
Melatonin solution helps treat hair loss in men and women.
research Dermoscopy: what's new?
Dermoscopy has improved skin cancer diagnosis and has expanding applications in dermatology, but requires staying updated with new research and techniques.
research Current management strategies for cutaneous T-cell lymphoma
The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.
research Human genetic basis of coronavirus disease 2019
Genetic differences affect COVID-19 severity and treatment development.
research Semiology of skin toxicity associated with epidermal growth factor receptor (EGFR) inhibitors
Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.
research Finasteride-associated male infertility
Finasteride may cause male infertility, stopping it can help.
research Current evaluation of amenorrhea
The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.