175 citations
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April 1982 in “Journal of The American Academy of Dermatology” Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.
165 citations
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September 2001 in “Genes & development” CDP is crucial for lung and hair follicle cell development.
146 citations
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May 2002 in “The American journal of pathology” Cathepsin L is essential for normal hair growth and development.
145 citations
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November 2018 in “Nature Communications” The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
130 citations
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January 2017 in “International journal of nanomedicine” Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.
122 citations
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June 2002 in “Genes & Development” Keratin 17 is crucial for early hair strength and cell survival.
108 citations
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July 2002 in “Molecular and cellular biology” Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.
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November 2011 in “Nature Communications” Wnt/β-catenin signaling is crucial for cell fusion in placental development.
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July 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.
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August 2002 in “Experimental Dermatology” Researchers developed a quick and easy way to get and grow cells from the base of human hair follicles.
71 citations
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January 2019 in “International journal of biological sciences” Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.
59 citations
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January 2013 in “Annals of Dermatology” Asian hair is more resistant to UV damage due to higher lipid content.
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September 1999 in “The journal of cell biology/The Journal of cell biology” K16 can partially replace K14 but causes hair loss and skin issues.
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August 2004 in “The FASEB Journal” Mice with human skin protein K8 had more skin problems and cancer.
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May 2003 in “Journal of Cell Science” α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.
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June 2009 in “Journal of Cosmetic Dermatology” Hair loss in males involves inflammation, collagen buildup, and follicle damage, with severity increasing with age and baldness duration.
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February 2002 in “International Journal of Dermatology” Permanent hair dye damages hair but it mostly recovers after 8 weeks; using certain hair care products can help repair it.
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May 2021 in “Nature communications” The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.
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December 2017 in “Advanced Healthcare Materials” Nanoencapsulation creates adjustable cell clusters for hair growth.
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April 2017 in “Journal of structural biology” Human hair keratin fibers have a detailed nano-scale structure that changes with different conditions.
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August 2019 in “Environmental research” Pseudomonas sp. T5-6-I bacteria increase selenium uptake in Brassica oleracea plants by 130%.
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December 2015 in “Journal of Materials Chemistry B” Scientists have created a method to deliver specific cells that can regenerate hair follicles, potentially offering a new treatment for hair loss.
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May 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” The type 3 IP3 receptor is important for controlling hair loss and growth.
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August 2014 in “Lipids” Human hair has more unsaturated fats inside than on the surface, and certain lipids may help bind the outer and inner layers together.
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November 2010 in “Journal of morphology” Antler velvet hair and body hair of red deer have different structures that help with protection and insulation.
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April 1978 in “Genetics Research” Mice with the ab gene have abnormal sebaceous gland development, affecting sebum production.
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July 2004 in “Journal of morphology” Monotreme hair structure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.
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January 2020 in “Biomaterials Science” Created microspheres show potential for safe and effective use in prostate artery embolization.
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October 2018 in “PloS one” Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.
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November 1987 in “Pediatric dermatology” Four children had unmanageable pale blond hair due to uncombable-hair syndrome.