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Glucocorticoids reduce fat production in liver cells, while androgens increase it in females; manipulating certain enzymes can influence these effects.

A new method was developed to measure and assess the activity and inhibition of the enzyme steroid 5α-reductase.

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

CYLD deficiency in skin tumors disrupts hair follicle cell processes and protein secretion.

A new treatment using nanoparticles can effectively prevent and reduce hair loss caused by chemotherapy.

Topical tacalcitol ointment can help improve symptoms of EFFC.

Clascoterone is safe for the heart, even at high doses.

The 736T>A mutation in the LIPH gene is common in Japanese people with autosomal recessive woolly hair.

CTCF protein is essential for skin and hair follicle development in mice.

5-Aminolevulinic acid can help chicken sperm move better at the right amount.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Using LC-MS/MS for hormone measurement can prevent false high testosterone results and avoid unnecessary tests.

The method accurately measures cyproterone acetate in plasma, showing no significant difference between two formulations.

Optimized liposomes can improve drug delivery and effectiveness.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

A new TP63 mutation was found in a baby with EEC syndrome, showing the need for TREC testing to check for immune issues.

Removing the liver tumor improved the patient's skin condition and hair growth.

Introducing the OTC gene improved symptoms in mice with OTC deficiency.

Eight blood metabolites are linked to causing allergic conjunctivitis, offering new ways to predict and treat it.

Early genetic testing and zinc therapy are crucial for managing acrodermatitis enteropathica effectively.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

Cronkhite-Canada syndrome may be more treatable and less severe than previously thought.

A new mouse mutation causes skin and hair defects due to a gene change.

High-throughput LC-MS screening is effective for finding new autotaxin inhibitors for asthma treatment.

Telitacicept helped stabilize complement levels in a patient with lupus and thyroid cancer.

Adding a second method to PROTACs could improve cancer treatment.

A patient with a PLEC mutation has epidermolysis bullosa, muscular dystrophy, and myasthenia gravis, which improved with steroid treatment.

Mixed coconut oil/solvent is suitable for cyproterone acetate injections, but more safety checks are needed.

The TIP1 gene is crucial for normal plant cell growth in Arabidopsis.

Being overweight, having gallbladder removal surgery, and taking cholesterol-lowering drugs are linked to a higher chance of getting vulvar lichen sclerosus.