245 citations
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January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
240 citations
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April 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
237 citations
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January 2010 in “The Journal of Sexual Medicine” The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.
237 citations
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December 2001 in “Urology” Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.
233 citations
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February 2018 in “Polymers” Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.
232 citations
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January 2013 in “Nature Cell Biology” Understanding where cancer cells come from helps create better prevention and treatment methods.
222 citations
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October 2014 in “Annual Review of Pharmacology and Toxicology” Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.
220 citations
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March 2020 in “Advanced functional materials” Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.
211 citations
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June 2012 The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
209 citations
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March 1989 in “Journal of The American Academy of Dermatology” Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.
192 citations
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January 2015 in “Journal of the American Academy of Dermatology” Targeted cancer therapies often cause serious skin problems that need careful management.
191 citations
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February 2002 in “Archives of Dermatology” Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.
183 citations
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January 2018 in “Cosmetics” Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.
165 citations
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September 2003 in “Toxicology and applied pharmacology” Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.
162 citations
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August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” The new "differential stripping" method effectively measures how much substance gets into hair follicles.
162 citations
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August 2002 in “Survey of Ophthalmology” Latanoprost can make eyelashes longer, thicker, and darker.
157 citations
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May 2021 in “Endocrine Reviews” Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.
156 citations
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August 2016 in “Journal of controlled release” Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
156 citations
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October 2012 in “Seminars in Cell & Developmental Biology” Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
151 citations
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May 2014 in “American Journal of Clinical Dermatology” Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.
150 citations
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December 2012 in “EMBO Reports” Stem cell self-renewal is complex and needs more research for full understanding.
147 citations
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January 2014 in “American Journal of Clinical Dermatology” Laser device increases hair density, safe for treating hair loss in men and women.
141 citations
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August 2018 in “Nature Reviews Microbiology” Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.
141 citations
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September 2016 in “European Journal of Dermatology” Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.
140 citations
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February 2020 in “Frontiers in Plant Science” RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.
140 citations
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January 2009 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Liposomes improve drug delivery and reduce skin irritation in dermatology.
132 citations
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August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
130 citations
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August 2020 in “Drug Design Development and Therapy” Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.
130 citations
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January 2017 in “International journal of nanomedicine” Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.
128 citations
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August 2015 in “Cell Stem Cell” Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.