24 citations
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January 1998 in “Dermatology” Merkel cell increase is specific to certain skin diseases, not general skin growth.
7 citations
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March 1993 in “International Journal of Oncology” Basal cell carcinoma shows keratin patterns similar to hair follicle structures.
3 citations
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July 2004 in “SKINmed/Skinmed” A 4-year-old girl was diagnosed with erythrokeratodermia variabilis after other treatments failed.
16 citations
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October 2014 in “Oral surgery, oral medicine, oral pathology and oral radiology” Keratoacanthoma comes from hair follicle cells.
23 citations
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February 2015 in “The American journal of pathology” Keratosis pilaris is often linked to genetic mutations and causes skin and hair abnormalities, regardless of those mutations.
23 citations
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February 1993 in “Journal of Investigative Dermatology” 44 citations
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January 2017 in “Journal of Investigative Dermatology” Mutations in the KLHL24 gene cause skin blistering in epidermolysis bullosa simplex.
13 citations
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November 1985 in “International Journal of Dermatology” The study found clear differences in lesion distribution and microscopic features among trichostasis spinulosa, keratosis pilaris, and eruptive vellus hair cysts.
59 citations
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August 1981 in “PubMed” Trichilemmal keratinization is a unique process in hair follicles where the outer root sheath turns into keratin without a specific layer.
September 2025 in “Annals of Plastic Surgery” Inverted follicular keratosis on the eyelid can be cured with surgery and has a great prognosis.
41 citations
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January 1992 in “Journal of medical genetics” The study found that males with KFSD had severe skin and eye symptoms, while female carriers had milder symptoms.
2 citations
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August 2016 in “Journal of Investigative Dermatology” 54 citations
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September 1999 in “PubMed” K15 staining helps distinguish basal cell carcinoma from trichoepithelioma.
63 citations
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July 2006 in “British Journal of Dermatology” Psoriasis causes changes in certain keratins and shrinks sebaceous glands in the scalp.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” HPV8 causes hair follicle stem cells to grow, leading to skin lesions.
12 citations
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March 2004 in “Journal of Investigative Dermatology”
March 2023 in “International journal of integrated medical research” Keratosis pilaris is a common skin condition where hair follicles get clogged with keratin, mostly on the arms and thighs.
January 2022 in “Clinical dermatology review” A girl with a rare skin condition called Keratosis Follicularis Spinulosa Decalvans showed no significant improvement with treatment.
7 citations
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March 2018 in “Experimental Dermatology” Acne lesions don't show increased keratinocyte growth compared to healthy hair follicles.
November 2023 in “Journal of Investigative Dermatology” Removing GRK2 in skin cells causes hair loss similar to immune-related alopecia.
1 citations
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January 2015 in “Journal of clinical case reports” KFSD causes scarring hair loss and skin roughness, mainly in males.
49 citations
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July 2006 in “British Journal of Dermatology” Calcifying epithelioma cells can differentiate into hair cortex and outer root sheath.
28 citations
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April 1996 in “Cell biology international” Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.
April 1996 in “Journal of Dermatological Science” October 2025 in “The Sri Lanka Journal of Dermatology” Inverted follicular keratosis can look like cancer but is actually a harmless tumor.
40 citations
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November 2021 in “International Journal of Molecular Sciences” Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.
22 citations
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February 2012 in “Journal of Investigative Dermatology” A specific gene mutation causes severe skin and nail issues and hair loss.
April 2013 in “Cancer Research” SKH1 hairless mice have identifiable epidermal stem cells with specific markers.
6 citations
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December 1990 in “PubMed” Keratinocytes in hair follicles differentiate similarly to skin cells, with specific patterns in different regions.
23 citations
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September 2014 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Laser treatments are the most effective for porokeratotic adnexal ostial nevus.