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Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Overexpression of the HE4 gene in mice causes eye inflammation and cloudiness.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

The document explains that hirsutism, often caused by hormonal issues, can be managed with treatment to improve both physical appearance and mental health.

The GH-IGF-I axis is likely involved in the hormonal imbalances seen in non-obese women with functional hyperandrogenism.

High-dose radioactive iodine therapy does not harm fertility in thyroidectomy patients.

Finasteride effectively treats mild to moderate hair loss in men aged 18-41, with some side effects.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Hibiscus rosa-sinensis may help treat various health issues and promote hair growth, but more research is needed for safety.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

Urologic diseases and treatments in older men can negatively affect fertility, and doctors should talk to patients about this.

Topical therapies show promise for hair loss and acne treatment with minimal side effects.

Men, particularly those with hair loss, are more likely to get the virus, and those with prostate cancer may have milder symptoms. Testosterone's role in the disease is unclear, and the virus doesn't seem to harm male fertility. Women with PCOS might be at higher risk. More research is needed.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

Excess androgens may cause PCOS, not just be a symptom.

Effective PCOS treatments require targeting specific signaling pathways.

A very low-calorie ketogenic diet led to weight loss and improved metabolic and hormonal health in obese men, with better sperm motility.

Hormonal status from androgen deprivation therapy may affect COVID-19 severity in men.

Air Vice-Marshal Sir Ralph Jackson significantly advanced dialysis technology in the UK.

Addressing underrepresentation in Parkinson's research is crucial for better treatments and understanding.

Finasteride reduces prostate size and PSA levels in young patients.

Age, race, family history, and certain genetic factors increase prostate cancer risk.

Low-glycemic index diets are beneficial for weight loss and satiety, but more research is needed on long-term effects and individualized approaches are recommended.

GnRH analogue can help diagnose ovarian causes of high testosterone in postmenopausal women when scans don't show the cause.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.