March 2024 in “Bioimpacts” 400 nm particles penetrate hair follicles best, but mouse models aren't fully reliable for human studies.
August 2023 in “Research Square (Research Square)” Two microRNAs affect hair follicle development in sheep by targeting specific genes.
Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.
July 2018 in “Elsevier eBooks” Some drugs can cause reversible hair loss, but certain chemotherapy drugs may lead to permanent hair loss; drugs can also change hair color and texture.
January 2017 in “Jikken doubutsu ihou/Jikken doubutsu/Experimental animals/Jikken Dobutsu” Mice with a changed Hr gene lose and regrow hair due to changes in the gene's activity.
Tissue from dog stem cells helped grow hair in mice.
Human scalp hair follicles have PGE2 and its receptors, which might affect hair growth.
Hair follicles can be used to quickly assess drug effects in cancer treatment.
Dermal stem cells help regenerate hair follicles and heal skin wounds.
Finasteride and low-level laser therapy are similarly effective for frontal pattern hair loss.
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
42 citations
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February 2017 in “Scientific Reports” Researchers found a way to create cells from stem cells that act like human cells important for hair growth and could be used for hair regeneration treatments.
13 citations
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January 2016 in “Journal of cosmetology & trichology” Alternative treatments show promise for hair growth beyond traditional methods.
7 citations
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May 2014 in “Clinical practice” Cooling the scalp may prevent hair loss from chemotherapy, hair often grows back after treatment, and nail issues usually improve after stopping the drug.
6 citations
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September 2015 in “Journal of Investigative Dermatology” Using special RNA to target a mutant gene fixed hair problems in mice.
2 citations
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January 2020 in “American Journal of Clinical Research and Reviews” All skin diseases might start in hair follicles.
24 citations
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February 2006 in “Chinese Medical Journal” Cultured dermal papilla cells can regenerate hair follicles and sustain hair growth.
17 citations
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June 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” The G60S Connexin43 mutation causes hair growth issues and poor hair quality in mice, similar to human ODDD patients.
14 citations
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February 2014 in “Experimental Cell Research” The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.
1 citations
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December 2010 in “InnovAiT” The document concludes that accurate diagnosis and appropriate management are crucial for treating various hair disorders, which have significant psychological impacts.
June 2018 in “Advances in Cosmetic Surgery” Hair loss caused by genetics and hormones; more research needed for treatments.
354 citations
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February 2011 in “Genes & Development” EZH1 and EZH2 are crucial for healthy hair growth and skin repair.
208 citations
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January 2013 in “Lab on a Chip” The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.
120 citations
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November 2014 in “Biological Reviews” The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
69 citations
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April 2019 in “Biomedicines” PRP and HF-MSCs treatment improves hair growth, thickness, and density in androgenetic alopecia.
60 citations
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November 2013 in “Development” Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.
56 citations
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May 2017 in “Nature Cell Biology” Hair can regrow after certain stem cells are lost because other stem cells can take over their role.
41 citations
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September 2011 in “Journal of Ethnopharmacology” Panax ginseng extract helps mice grow hair.
40 citations
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June 2009 in “Journal of Cutaneous Pathology” AGA patients have fewer hairs and smaller follicles; T:V ratio above 4:1 may indicate AGA.
40 citations
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November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” S100A3 protein is crucial for hair shaft formation in mice.