research Oral syphilis: report of three cases and characterization of the inflammatory cells
The document concludes that recognizing oral lesions is important for diagnosing syphilis.
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research Controversies Regarding Transdermal Androgen Therapy in Postmenopausal Women
Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.
research ANDROGENETIC ALOPECIA
Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.
research Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation
Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.
research Cystathionine β‐synthase‐deficient mice thrive on a low‐methionine diet
Mice with CBS deficiency are healthier on a low-methionine diet.
research Polycystic ovary syndrome is associated with atherogenic changes in lipoprotein particle number and size independent of body weight
Women with PCOS have unhealthy changes in their cholesterol particles that are not related to their body weight.
research Cell Cycle Regulation and Regeneration
Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
research Prescribing testosterone and DHEA: The role of androgens in women
Testosterone and DHEA can benefit women's health but must be prescribed carefully due to potential risks.
research Transdermal Composite Microneedle Composed of Mesoporous Iron Oxide Nanoraspberry and PVA for Androgenetic Alopecia Treatment
Microneedle made of iron oxide and PVA helps hair regrowth in alopecia treatment.
research Efficacy and Safety of Oral Minoxidil 5 mg Once Daily in the Treatment of Male Patients with Androgenetic Alopecia: An Open-Label and Global Photographic Assessment
Oral minoxidil 5 mg daily increases hair growth safely in men with hair loss, with minor side effects.
research Polycystic ovary syndrome and risks for COVID-19 infection: A comprehensive review
Women with PCOS have a higher risk of severe COVID-19 due to related health issues.
research The efficacy and use of finasteride in women: a systematic review
Finasteride improves hair growth and reduces hirsutism in women, but side effects and optimal dosages need further research.
research Multi‐tasking epidermal stem cells: Beyond epidermal maintenance
Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.
research Expression of Kruppel-Like Factor KLF4 in Mouse Hair Follicle Stem Cells Contributes to Cutaneous Wound Healing
KLF4 is important for maintaining skin stem cells and helps heal wounds.
research Human placental extract exerts hair growth-promoting effects through the GSK-3β signaling pathway in human dermal papilla cells
Human placental extract may help hair growth by affecting certain cell signals and could be more effective with minoxidil.
research Novel inhibitors of 5α-reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
research Betaine supplementation is less effective than methionine restriction in correcting phenotypes of CBS deficient mice
Methionine restriction works better than betaine for treating CBS deficiency symptoms in mice.
research Impact of Treatment with Rosiglitazone or Metformin on Biomarkers for Insulin Resistance and Metabolic Syndrome in Patients with Polycystic Ovary Syndrome
Rosiglitazone may be better than metformin for insulin resistance in PCOS, but more research is needed on certain biomarkers.
research Adrenal Gland Disease in Ferrets
Adrenal gland disease is common in ferrets and causes hair loss and other symptoms.
research Molecular Genetics of Keratinization Disorders – What’s New About Ichthyosis
Over 67 genes linked to ichthyosis help improve diagnosis and treatment.
research How to Diagnose and Treat Medically Women with Excessive Hair
Treating excessive hair in women requires a holistic approach, including medical, aesthetic, and emotional support.
research Women’s Health Care During the Perimenopause
The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.
research Pre-aggregation of scalp progenitor dermal and epidermal stem cells activates the WNT pathway and promotes hair follicle formation in in vitro and in vivo systems
Grouping certain skin cells together activates a growth pathway that helps create new hair follicles.
research Candidate SNP markers of reproductive potential are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters
Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.
research Metabolic Syndrome and Insulin Resistance Syndrome among Infertile Women with Polycystic Ovary Syndrome: A Cross-Sectional Study from Central Vietnam
Many infertile women with PCOS in Central Vietnam have metabolic or insulin resistance syndrome, with obesity and older age increasing the risk.
research Worth a Second Look
A 72-year-old man had severe fatigue, weight loss, and frequent loose stools.
research Trichoblastoma with sebaceous and sweat gland differentiation
A rare benign skin tumor showed unusual features of sebaceous and sweat glands, important for correct diagnosis.
research Effects of strain and age on ear wound healing and regeneration in mice
Young C57BL/6 mice heal better than BALB/c mice, and older mice heal faster but regenerate worse.
research Polycystic ovary syndrome
PCOS is a common hormonal disorder in women, treated with lifestyle changes, medication, and patient education.
research Male, Female, Other: Transgender and the Impact in Primary Care
Healthcare providers need better education and resources to give competent and sensitive care to transgender patients.