May 1993 in “Drugs & Therapy Perspectives” Formestane is a preferred second-line treatment for advanced breast cancer in postmenopausal women because it's effective and has fewer side effects.
March 2024 in “BMC women's health” The levonorgestrel implant increases free testosterone and lowers SHBG more than DMPA-IM and the copper IUD.
April 2020 in “Research Square (Research Square)” Oral contraceptives with cyproterone acetate improved quality of life for women with PCOS more than those with levonorgestrel.
August 2016 in “Journal of Investigative Dermatology”
115 citations
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January 2001 in “American journal of clinical dermatology” Eflornithine cream effectively reduces women's unwanted facial hair but hair returns if treatment stops.
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January 1991 in “Journal of dermatological treatment” Goserelin and oestradiol treatment slightly improved hairiness but did not significantly change sebum production or hair characteristics in mildly hirsute women.
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January 1980 in “PubMed” Oral contraceptives can cause nausea, headaches, mood changes, and other side effects, especially early on.
Spironolactone is a promising alternative to antibiotics for treating acne in adult females.
5 citations
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January 2007 in “Immunopharmacology and Immunotoxicology” 17β-Estradiol boosts allergic reactions and slows thymus aging in mice.
May 2021 in “Journal of the Endocrine Society” Transgender females can reach their target estrogen levels using estradiol patches, especially if oral treatments fail or if they're at risk for blood clots. Often, the highest dose patch is needed.
11 citations
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November 2009 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.
October 2022 in “Journal of the ASEAN Federation of Endocrine Societies” GnRH-a or orchiectomy is more effective than anti-androgens for managing hormone levels in transgender women.
September 2021 in “GLOBAL JOURNAL FOR RESEARCH ANALYSIS” The hormonal contraceptive combination effectively reduces androgen excess and improves PCOS symptoms like acne, hair loss, and menstrual issues.
1 citations
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March 2012 in “Journal of Dermatological Science” Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.
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May 2017 in “The journal of sexual medicine” Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.
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June 2012 in “Human Reproduction Update” The conclusion is that there is a high demand for new contraceptives that provide both pregnancy prevention and protection against STIs, along with additional health benefits.
January 2002 in “NCSU Libraries Repository (North Carolina State University Libraries)” 17b-Estradiol in skin affects hair growth and tumor promotion.
March 2019 in “Reactions Weekly” Injection contraception has more negative side effects than hormonal pills.
October 2025 in “Journal of the Endocrine Society” The patient was satisfied with hormone therapy, and her epilepsy remained stable.
October 2024 in “Clinical and Experimental Dermatology” The combination treatment didn't work better than minoxidil alone and caused more menstrual issues.
3 citations
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July 2009 in “Experimental and Clinical Endocrinology & Diabetes” Low-dose Buserelin effectively reduces hirsutism with minimal side effects.
June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” 17α-estradiol extends lifespan and improves metabolism in male mice through the estrogen receptor α.
1 citations
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September 2025 in “International Journal of Drug Delivery Technology” Ecklonia cava improves the effectiveness of Diane-35 in managing PCOS symptoms.
Neurosteroids help regulate oxytocin levels, especially during stress and pregnancy, to protect against premature labor.
29 citations
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March 2017 in “International Journal of Women's Dermatology” Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.
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June 2015 in “British Journal of Dermatology” Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.
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May 2004 in “Journal der Deutschen Dermatologischen Gesellschaft” Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.
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August 2006 in “International Journal of Pharmaceutics” The eucalyptus oil system improved skin delivery of hormones, but safety concerns remain.
June 2022 in “Zenodo (CERN European Organization for Nuclear Research)”