research Dihydrotestosterone-induced hair regrowth inhibition by activating androgen receptor in C57BL6 mice simulates androgenetic alopecia
DHT stops hair regrowth in mice, similar to human hair loss.
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research Regenerative medicine and hair loss: how hair follicle culture has advanced our understanding of treatment options for androgenetic alopecia
Hair follicle culture helps develop new treatments for hair loss.
research Progesterone-induced stimulation of mammary tumorigenesis is due to the progesterone metabolite, 5α-dihydroprogesterone (5αP) and can be suppressed by the 5α-reductase inhibitor, finasteride
Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.
research The Utility of Metformin Therapy in Reproductive-Aged Women with Polycystic Ovary Syndrome (PCOS)
Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.
research Recent discoveries and developments of androgen receptor based therapy for prostate cancer
New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.
research Mouse Spermatogenesis Reflects the Unity and Diversity of Tissue Stem Cell Niche Systems
Mouse spermatogenesis shows that stem cells can behave flexibly and move widely in open environments.
research Menopausal Acne – Challenges And Solutions
Menopausal acne is treated with medications and lifestyle changes, but careful choice is needed due to side effects.
research Trends in the Development of New Drugs for Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.
research The nutritional biochemistry of wool and hair follicles
Nutrients like vitamins, copper, zinc, and amino acids are crucial for healthy hair and wool growth.
research Induction of Hair Keratins Expression by an Annurca Apple-Based Nutraceutical Formulation in Human Follicular Cells
An apple-based supplement was found to stimulate hair protein production, which may help with hair growth.
research Biology of Human Hair: Know Your Hair to Control It
Understanding hair biology is key to developing better treatments for hair and scalp issues.
research Male fertility and skin diseases
Some skin diseases and their treatments can negatively affect male fertility.
research Drug eruptions in dermatology
Skin reactions to drugs are common and can be deadly, usually requiring stopping the drug and may be better prevented with genetic testing in the future.
research Improving selective androgen receptor modulator discovery and preclinical evaluation
We need better ways to test and understand SARMs to make safer and more effective treatments.
research Endocrine treatment of benign prostatichypertrophy: Current concepts
New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.
research Integral Roles of Specific Proteoglycans in Hair Growth and Hair Loss: Mechanisms behind the Bioactivity of Proteoglycan Replacement Therapy with Nourkrin® with Marilex® in Pattern Hair Loss and Telogen Effluvium
Proteoglycans are important for hair growth, and a specific treatment can help reduce hair loss.
research Hyperandrogenism in Adolescent Girls
Diagnosing PCOS in teenage girls is tricky and requires careful evaluation and management.
research The ‘bald’ phenotype (androgenetic alopecia) is caused by the high glycaemic, high cholesterol and low mineral ‘western diet’
Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.
research Inhibition of 5α-reductase alters pregnane metabolism in the late pregnant mare
Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.
research Endocrinopathies and Other Disorders Inducing a Polycystic Ovary Syndrome Phenotype
Some conditions mimic PCOS symptoms and need careful diagnosis to treat potentially serious health issues.
research The Postnatal Offspring of Finasteride-Treated Male Rats Shows Hyperglycaemia, Elevated Hepatic Glycogen Storage and Altered GLUT2, IR, and AR Expression in the Liver
Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.
research Hair in health and disease: an introduction
Hair health depends on various factors and hair loss can significantly affect a person's well-being; understanding hair biology is key for creating effective hair care treatments.
research Complementary evolution of coding and noncoding sequence underlies mammalian hairlessness
Hairless mammals have genetic changes in both their protein-coding and regulatory sequences related to hair.
research SUPEROXIDE DISMUTASE LOADED NIOSOMES DELIVERY TO HAIR FOLLICLES: PERMEATION THROUGH SYNTHETIC MEMBRANE AND GUINEA PIG SKIN
Niosomes can effectively deliver Superoxide Dismutase to hair follicles, potentially helping prevent hair loss.
research Finasteride and Methadone Use and Risk of Advanced Hepatitis C Related Liver Disease
Finasteride and methadone don't increase advanced liver disease risk in HCV+ male veterans.
research Polycystic ovarian syndrome
PCOS is a common hormonal disorder in women that can lead to serious health problems.
research Evaluation Asprosin Level in Polycystic Ovary Syndrome and Its Association with Fetuin a and Some Biochemical Parameter
Fetuin A levels are higher in PCOS patients, while asprosin levels show no difference.
research Paternal Finasteride Treatment Can Influence the Testicular Transcriptome Profile of Male Offspring—Preliminary Study
Father's finasteride use may affect son's fertility and testicular function.
research Effect of herbal mixture (RAA) on hair growth in C57BL/6 mice
The herbal mixture RAA promotes hair growth and could be an alternative treatment for hair loss.
research Pathogenesis and causes of hirsutism
Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.