research Clinical relevance of testosterone and dihydrotestosterone metabolism in women
Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.
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research Testosterone implants in women: Pharmacological dosing for a physiologic effect
Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.
research Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride
Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.
research Prescribing testosterone and DHEA: The role of androgens in women
Testosterone and DHEA can benefit women's health but must be prescribed carefully due to potential risks.
research Modulating testosterone pathway: a new strategy to tackle male skin aging?
Honokiol might help reduce male skin aging by maintaining testosterone levels.
research Protective role of agomelatine via modulation of TLR4/NF-κB: NLRP3/IL-1β signaling pathways in testosterone-induced benign prostatic hyperplasia in rats
Agomelatine may help reduce benign prostatic hyperplasia by blocking certain inflammatory pathways.
research Evaluating Testosterone and Dehydroepiandrosterone Sulfate (DHEA-S) as Biomarkers for Male Androgenetic Alopecia
Higher testosterone and DHEA-S levels may be linked to male pattern baldness.
research Behavioral and hormonal changes following the continuous administration of testosterone in females in capuchin monkey adult females (Sapajus Libidinosus)
Testosterone increases sexual behavior in female capuchin monkeys.
research Effect of High Levels of Testosterone on Cardiovascular Risk in Polycystic Ovary Syndrome (PCOS)
High testosterone increases heart disease risk in women with PCOS.
research ORIGINAL RESEARCH—ENDOCRINOLOGY: Comparison of the Steady‐State Pharmacokinetics, Metabolism, and Variability of a Transdermal Testosterone Patch Versus a Transdermal Testosterone Gel in Hypogonadal Men
The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.
research Review Article: Practical Aspects of Testosterone Deficiency Syndrome in Clinical Urology
Testosterone replacement therapy improves libido, mood, muscle strength, and bone density in men with Testosterone Deficiency Syndrome.
research Prostate-Sparing Effects in Primates of the Potent Androgen 7α-Methyl-19-Nortestosterone: A Potential Alternative to Testosterone for Androgen Replacement and Male Contraception1
MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.
research Hyperandrogenism in a Postmenopausal Woman Secondary to Testosterone Secreting Ovarian Stromal Tumor with Acoustic Schwannoma
A 63-year-old woman's male-like symptoms were caused by a rare testosterone-producing ovarian tumor, treated by removing her ovaries and fallopian tubes.
research Detection of cortisol, estradiol, and testosterone in archaeological human hair from the Dakhleh Oasis, Egypt
Ancient hair can preserve hormones, revealing health and fertility insights.
research Administration of Caesalpinia bonduc Seed Extracts Ameliorates Testosterone-Induced Benign Prostatic Hyperplasia (BPH) in Male Wistar Rats
Caesalpinia bonduc seed extracts may help treat enlarged prostate in rats.
research A model system for long-term serum-free suspension organ culture of human fetal tissues: experiments on digits and skin from multiple body regions
Scientists developed a method to grow human fetal skin and digits in a lab for 3-4 weeks, which could help study skin features and understand genetic interactions in tissue formation.
research Effect of Eurycoma longifolia Extract on Testosterone Synthesis in TM3 Leydig Cells under Oxidative Stress
Eurycoma longifolia extract may help increase testosterone levels and reduce andropause symptoms.
research Plasma Diaphanous Related Formin 1 Levels Are Associated with Altered Glucose Metabolism and Insulin Resistance in Patients with Polycystic Ovary Syndrome: A Case Control Study
Women with Polycystic Ovary Syndrome (PCOS) have lower levels of a substance called DIAPH1 in their blood, which is linked to changes in sugar metabolism and insulin resistance.
research The hyperandrogenic-insulin-resistant acanthosis nigricans syndrome: therapeutic response
Most patients improved with oral contraceptives, but some needed additional treatment.
research Hirsutism in the Adolescent Female
The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.
research Adverse effects of common medications on male fertility
Some common medications can harm male fertility, but many effects can be reversed.
research MENSTRUAL DISORDERS IN ADOLESCENTS
The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.
research The genetics of androgenetic alopecia
Genes and hormones cause hair loss, with four genes contributing equally.
research An Unusual Case of Thalamic Stroke in a Young Adult With Patent Foramen Ovale and Finasteride Use
Stopping finasteride and closing PFO can help prevent strokes in young adults.
research Finasteride for female androgenetic alopecia
Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.
research A woman with iatrogenic androgenetic alopecia responding to finasteride
EF and PXE not closely related.
research Testicular Steroidogenesis
Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.
research Local synthesis and function of neuro-estrogen and neuro-androgen: impact on the hippocampus-related cognition and neuronal plasticity
Neurosteroids like neuro-estrogen and neuro-androgen are crucial for brain function and can improve cognition and protect against aging-related decline.
research Cross-sex hormone therapy for gender dysphoria
Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.
research Epidemiology, diagnosis and management of hirsutism: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome Society
Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.