99 citations
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October 2006 in “BMC clinical pharmacology” Finasteride may cause slight depression and anxiety.
93 citations
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June 2001 in “The Journal of Clinical Endocrinology and Metabolism” Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.
84 citations
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December 2018 in “Genetics in Medicine” Pegvaliase is recommended for treating adults with phenylketonuria.
81 citations
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May 2007 in “Fertility and Sterility” Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.
77 citations
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July 2013 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.
76 citations
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December 2009 in “Clinics in Dermatology” Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.
66 citations
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January 2017 in “Acta dermato-venereologica” Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
63 citations
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December 2002 in “Archives of Dermatology” The 308-nm excimer laser is a promising treatment for vitiligo with varying success and mild side effects.
62 citations
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February 2011 in “Expert review of dermatology” Scalp cooling can reduce chemotherapy-induced hair loss and should be available in all hospitals.
60 citations
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January 2023 in “Biogerontology” Adequate testosterone is crucial for men's health and quality of life, but its decline with age needs more research.
58 citations
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December 2012 in “Aaps Pharmscitech” LCN may improve finasteride delivery for hair loss treatment.
52 citations
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November 2013 in “European Journal of Pharmaceutical Sciences” Chitosan-decorated polymersomes improve finasteride delivery for hair loss treatment.
50 citations
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May 2019 in “Drugs” Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.
48 citations
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June 2013 in “Journal of Dermatological Science” Valproic acid may help hair grow and could be a safe treatment for hair loss.
47 citations
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October 2014 in “Expert Opinion on Emerging Drugs” New alopecia treatments aim for better results and fewer side effects.
46 citations
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January 2008 in “Climacteric” Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.
42 citations
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July 2015 in “Cosmetics” Nanotechnology improves hair care products by enhancing ingredient stability, targeting treatment, and reducing side effects, but more research on its toxicity is needed.
40 citations
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December 2012 in “Epilepsia” Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.
40 citations
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July 2007 in “Dermatologic Therapy” Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.
39 citations
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October 2015 in “Case Reports” Some people experience severe, long-lasting side effects from fluoroquinolone antibiotics, leading to the recommendation of limited use and increased awareness of these risks.
38 citations
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January 2001 in “Neuroepidemiology” The current system can't fully test all combination treatments, so alternative methods and regulatory flexibility are needed.
37 citations
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February 2013 in “Maturitas” Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.
37 citations
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June 2011 in “Journal of Cellular Biochemistry” Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
35 citations
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August 2004 in “Epilepsy & behavior” Extended-release divalproex is better tolerated and more effective for seizures and psychiatric symptoms than delayed-release divalproex, but doesn't reduce hair loss.
34 citations
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May 2017 in “Seminars in Reproductive Medicine” Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.
33 citations
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April 2015 in “Current Opinion in Endocrinology, Diabetes and Obesity” 5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.
31 citations
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January 2017 in “Phytotherapy Research” Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.
31 citations
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September 2012 in “Human Brain Mapping” People with Seasonal Affective Disorder have different brain activity in certain areas when resting.
30 citations
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June 2019 in “Frontiers in Endocrinology” The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.
30 citations
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March 2015 in “Clinical Endocrinology” Young women with high male hormone levels or PCOS often feel more psychological distress and have a lower quality of life.