research Differential association between cumulative dose of 5α-reductase inhibitors and mortality
Higher doses of 5α-reductase inhibitors may lower mortality risk, but low doses increase it.
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research All sites but skin cancer incidences analyzed worldwide by sex, age, and skin type over time (1955-2007), advancing age, and UVB dose reveals important carcinogenic drivers
Cancer rates are increasing in developed countries, with estrogen, aging, low vitamin D3, and HPV infection as common causes.
research Tamsulosin treatment for benign prostatic hyperplasia and risk of severe hypotension in men aged 40-85 years in the United States: risk window analyses using between and within patient methodology
Tamsulosin for enlarged prostate may increase the risk of severe low blood pressure, especially when starting or restarting the medication.
research Basic research in biostimulation
Low-output laser irradiation can stimulate or inhibit biological processes depending on the dose.
research Recomendaciones sobre el manejo clínico de la alopecia androgénica: un documento de consenso del Grupo Español de Tricología de la Academia Española de Dermatología y Venereología
Dermatologists recommend oral dutasteride for male hair loss, low-dose oral minoxidil for female hair loss, and a multidisciplinary approach for young patients, with caution during pregnancy.
research Clinical and genetic findings in a Chinese family with VDR-associated hereditary vitamin D-resistant rickets
A Chinese family had a child with a specific gene mutation causing vitamin D-resistant rickets, but the child improved with calcium and low-dose calcitriol.
research Primary Generalized Glucocorticoid Resistance or Chrousos Syndrome: Allostasis Through a Mutated Glucocorticoid Receptor
Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.
research Mixed “Antiandrogenic” Chemicals at Low Individual Doses Produce Reproductive Tract Malformations in the Male Rat
Low doses of mixed chemicals cause permanent reproductive malformations in male rats.
research Low-Level Laser Therapy (LLLT) in Wound Healing
Low-Level Laser Therapy helps heal wounds and regenerate tissue when used correctly.
research G42 Long term safety and efficacy of single dose parenteral iron in children with inflammatory bowel disease in a large tertiary centre
Single-dose parenteral iron is safe and effective for children with inflammatory bowel disease and iron-deficiency anemia.
research Low Molecular Weight Collagen Peptide (LMWCP) Promotes Hair Growth by Activating the Wnt/GSK-3β/β-Catenin Signaling Pathway
A type of collagen helps hair grow by boosting cell growth and activating a specific hair growth pathway.
research THU0239 Methotrexate Dose has Minimal Effects on Methotrexate-Related Toxicity in Patients with Early Rheumatoid Arthritis Treated in Combination with Adalimumab – Results of Concerto Trial
Methotrexate dose has little effect on its toxicity when used with adalimumab for early rheumatoid arthritis.
research Testosterone for Low Libido in Postmenopausal Women Not Taking Estrogen: A Phase III Research Study of Female Sexual Dysfunction in Women on Testosterone Patch Without Estrogen (APHRODITE)
Testosterone patches can modestly improve sexual function in postmenopausal women not on estrogen therapy.
research Comprehensive Safety Exposure‐Response Analysis to Support Ritlecitinib Dose Selection
A 50 mg non-loading dose of ritlecitinib is safe for adults and adolescents.
research Inactivated COVID-19 Vaccine Induces a Low Humoral Immune Response in a Subset of Dermatological Patients Receiving Immunosuppressants
Some patients on immunosuppressants had a weaker immune response to the Sinovac-CoronaVac COVID-19 vaccine.
research Successful treatment of resistant alopecia areata with a phototoxic dose of ultraviolet A after topical 8‐methoxypsoralen application
This therapy effectively treats resistant alopecia areata with minimal side effects.
research Abstract 313: Finasteride Delays Atherosclerosis Progression and Reduces Hepatic Inflammation in Low-density Lipoprotein Receptor-deficient Mice
Finasteride may slow down heart disease by lowering cholesterol and reducing inflammation.
research Iron Supplementation May Improve the Patient’s Level of Satisfaction in Not-Low-Ferritin Telogen Effluvium: A Real-Life Observational Study
Iron supplements may improve hair loss satisfaction even if initial iron levels are normal.
research Disorders of sex development (DSD) 46.XY due to type 2 5-α reductase deficiency in three siblings: Case report from a low-resource setting
Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.
research Acceptance of COVID-19 Vaccine Booster Doses Using the Health Belief Model: A Cross-Sectional Study in Low-Middle- and High-Income Countries of the East Mediterranean Region
People in high-income countries are more likely to accept COVID-19 booster doses than those in middle or low-income countries.
research Characterization of Cutaneous Photoxicity Induced by Topical Alpha-Terthienyl and Ultraviolet A Radiation
Low-dose topical alpha-terthienyl may be a safer option for treating skin conditions with light therapy.
research Medical treatment regimens of hirsutism
Low-dose anti-androgen drugs and certain drug combinations are effective for hirsutism, and insulin sensitizers show promise, especially for those with polycystic ovarian syndrome.
research Female pattern hair loss
Low-dose oral minoxidil effectively reduces hair loss in women with female pattern hair loss.
![Minoxidil and Its Use in Hair Disorders: A Review [Corrigendum]](/images/research/d5b5fb1b-96a4-4e61-a554-3fe9a1f78497/small/11472.jpg)
research Minoxidil and Its Use in Hair Disorders: A Review [Corrigendum]
Low-dose Minoxidil combined with Spironolactone helps reduce hair loss and improve hair density in women, with some mild side effects.
research Fundamental research on the action mechanism of the 800 nm semiconductor laser on skin blackheads and coarse pores
Low-dose 800 nm laser effectively treats blackheads and coarse pores without harming cell growth.
research Oral Minoxidil for Alopecia Treatment: Risks, Benefits, and Recommendations
Low-dose oral minoxidil can effectively promote hair growth but requires careful monitoring for safety.
research Eficácia Do Minoxidil Tópico E Oral No Tratamento Da Alopecia Androgenética
Low-dose oral minoxidil is as effective as or better than topical minoxidil for hair growth but may cause mild side effects.
research Scarring Alopecias in a Pediatric Trichology Clinic at a Tertiary Care Center
Low-dose isotretinoin is effective for treating pediatric scarring alopecia.
research Pericardial Disorders Occurring during Open Label Study of 3747 Patients Treated with Systemic Minoxidil
Low-dose oral minoxidil is safe for the heart.
research Minoxidil oral en dosis bajas en alopecia frontal fibrosante: serie de 122 pacientes
Low-dose oral minoxidil can improve hair and eyebrow growth in frontal fibrosing alopecia.