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research
L-Cystine-Containing Hair-Growth Formulation Supports Protection, Viability, and Proliferation of Keratinocytes

2 citations , August 2020 in “Clinical, Cosmetic and Investigational Dermatology”

The hair-growth formula with L-cystine helps protect and grow hair cells.

research Medicinal Uses of L-Lysine: Past and Future

14 citations , October 2011

L-Lysine may help with various health conditions, but results are inconsistent for herpes treatment and its potential in other therapies is still being explored.

research Abstract 94: Hyaluronan Synthase 2 Knock Down in Epidermis Alter Wound Healing and Hair Follicle Development

April 2017 in “Plastic & Reconstructive Surgery Global Open”

Hyaluronan from Has2 is important for proper wound healing and hair follicle development.

research A Variable Monilethrix Phenotype Associated With a Novel Mutation, Glu402Lys, in the Helix Termination Motif of the Type II Hair Keratin hHb1

47 citations , July 1998 in “Journal of Investigative Dermatology”

A new mutation, Glu402Lys, in hair keratin is linked to variable symptoms of monilethrix.

research
Effect of Hyaluronic Acid and Poly-L-Lactic Acid Dermal Fillers on Collagen Synthesis: An in vitro and in vivo Study

34 citations , September 2020 in “Clinical, cosmetic and investigational dermatology”

Hyaluronic acid increases collagen synthesis safely, while poly-L-lactic acid may cause complications by affecting fibroblasts.

research Metabolic and pathologic profiles of human LSS deficiency recapitulated in mice

23 citations , February 2020 in “PLOS genetics”

Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.

research The β9 Loop Domain of PA-PLA1α Has a Crucial Role in Autosomal Recessive Woolly Hair/Hypotrichosis

11 citations , April 2012 in “Journal of Investigative Dermatology”

A specific mutation in PA-PLA1α causes abnormal hair growth.

Complete Defect in PA-PLA1α Secretion Function Leading to Autosomal Recessive Woolly Hair and Hypotrichosis: Insights from a Novel Compound Heterozygous LIPH Variant Study in a Chinese Pedigree

research Complete defect in PA-PLA1α secretion function leading to autosomal recessive woolly hair and hypotrichosis: insights from a novel compound heterozygous LIPH variant study in a Chinese pedigree

May 2025 in “Frontiers in Genetics”

A new genetic variant in the LIPH gene causes hair growth issues in a Chinese patient.

research 144 Deciphering the role of the hexosamine pathway in skin homeostasis

August 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

The hexosamine pathway helps protect skin cells from stress and may improve skin and hair health.

research Identification of 736T>A mutation of lipase H in Japanese siblings with autosomal recessive woolly hair

7 citations , February 2011 in “Journal of dermatology”

The 736T>A mutation in the LIPH gene is common in Japanese people with autosomal recessive woolly hair.

research Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice

5 citations , September 2018 in “International journal of genomics”

Genetic mutations that disrupt homocysteine breakdown lead to increased damage in mouse hair keratin.

research Structural Stability of Wild Type and Mutated α-Keratin Fragments: Molecular Dynamics and Free Energy Calculations

40 citations , September 2004 in “Biomacromolecules”

The Glu413Lys mutation in keratin affects hair stability, while Glu413Asp does not.

research 597 Outer root sheath is able to synthesise glycogen from lactate-investigating glycogen metabolism in human hair follicles

7 citations , September 2019 in “Journal of Investigative Dermatology”

research De novo mutations in monilethrix

26 citations , December 2003 in “Experimental Dermatology”

Specific keratin gene mutations can cause monilethrix.

research Metabolism of Freshly Isolated Human Hair Follicles Capable of Hair Elongation: A Glutaminolytic, Aerobic Glycolytic Tissue

71 citations , June 1993 in “Journal of Investigative Dermatology”

research Metabolic Engineering of Microorganisms to Produce L-Aspartate and Its Derivatives

August 2023 in “Fermentation”

Scientists can use engineered microbes to make L-aspartate and related chemicals, but there's still room to improve their efficiency.

research Hydrolyzed Hair Keratin

January 2007

research Omega-6 highly unsaturated fatty acids in Leydig cells facilitate male sex hormone production

7 citations , September 2022 in “Communications biology”

Omega-6 fats in certain cells boost male hormone production.

research Type II Keratins Are Phosphorylated on a Unique Motif during Stress and Mitosis in Tissues and Cultured Cells

80 citations , June 2002 in “Molecular Biology of the Cell”

Type II keratins are uniquely phosphorylated during stress and mitosis, affecting their structure and function.

research STEEL. IN: STRUCTURAL CONDITION ASSESSMENT

January 2005 in “Life sciences”

Targeting LPA could help treat skin disorders.

research 130 Deciphering the role of the hexosamine pathway in skin homeostasis

September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

The hexosamine pathway helps maintain healthy skin by affecting the skin's structure and possibly increasing hair follicle stem cells.

research 1332 Understanding the role of glycogen metabolism in human hair follicle biology

April 2018 in “Journal of Investigative Dermatology”

Glycogen metabolism is important for energy and processes in human hair follicles, and hair follicles may produce glucose from lactate.

research Synthesis and biological evaluation of dimeric peptide derivatives as proliferation‐stimulating agents in human follicle dermal papilla cells

3 citations , September 2021 in “Bulletin of the Korean Chemical Society”

Dimeric peptide derivatives could help hair growth and treat hair loss safely.

research Nε-(carboxymethyl) lysine represses hair follicle formation by inhibiting Sonic hedgehog expression in a NF-κB-independent manner

January 2019 in “Proceedings for Annual Meeting of The Japanese Pharmacological Society”

Nε-(carboxymethyl) lysine delays hair growth by blocking a key protein.

research Synthesis, antiproliferative, acute toxicity and assessment of antiandrogenic activities of some newly synthesized steroidal lactams

23 citations , February 2010 in “European Journal of Medicinal Chemistry”

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