266 citations
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November 2013 in “European Journal of Epidemiology” The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.
247 citations
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August 2011 in “European Journal of Epidemiology” The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.
202 citations
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August 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
181 citations
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January 2009 in “Nature Genetics” Certain mutations in a hair growth-related gene cause a type of genetic hair loss.
179 citations
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March 2005 in “British Journal of Dermatology” Oral antiandrogens effectively treat female hair loss, with better results in higher hair loss grades.
172 citations
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December 2004 in “Journal of The American Academy of Dermatology” Demodicosis is common and often missed, needing more recognition and treatment in skin care.
120 citations
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October 2007 in “Clinical Interventions in Aging” Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.
82 citations
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April 1981 in “Clinical endocrinology” A girl with rickets and hair loss was found to have a rare condition where her body didn't respond to vitamin D treatment.
81 citations
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September 2005 in “The American journal of pathology” Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.
71 citations
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July 2015 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.
68 citations
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June 2005 in “Expert Opinion on Therapeutic Targets” Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
67 citations
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August 2007 in “American Journal of Pathology” Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
66 citations
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July 2015 in “Organogenesis” Wnt signaling is crucial for skin wound healing and reducing scars.
66 citations
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March 2009 in “British journal of surgery” Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.
54 citations
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May 2018 in “Journal of The European Academy of Dermatology and Venereology” Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.
44 citations
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July 1990 in “Journal of the American College of Cardiology” Captopril reduces heart mass, while minoxidil has opposite effects and side effects.
34 citations
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January 2005 in “Journal of the American Veterinary Medical Association” Cyclosporine A can reduce inflammation in dogs with sebaceous adenitis, but ongoing treatment is needed.
27 citations
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December 2013 in “Endocrinology” Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.
26 citations
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January 1978 in “Nephron” Minoxidil lowers blood pressure effectively but may cause side effects.
23 citations
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September 2011 in “Journal of Dermatological Science” Red LED light helps mouse hair grow by increasing growth factors from skin cells.
22 citations
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November 2013 in “Clinical and experimental dermatology (Print)” Ecklonia cava, a type of seaweed, may help hair grow.
21 citations
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July 2019 in “Cardiovascular Research” High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.
20 citations
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May 2020 in “Experimental Dermatology” Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.
20 citations
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February 1977 in “Circulation” Minoxidil lowers blood pressure and increases heart efficiency, but may raise lung artery pressure in some people.
17 citations
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December 2001 in “Journal of Investigative Dermatology” The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.
16 citations
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June 2021 in “Journal of Dermatological Treatment” Minoxidil effectively treats hair loss, especially androgenetic alopecia, but needs more research for better understanding.
15 citations
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May 2010 in “Actas Dermo-Sifiliográficas” Balding men have higher heart disease risk.
15 citations
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January 2010 in “Experimental Dermatology” Hair loss in certain young mice is linked to a specific gene and can be caused by lack of iron.
14 citations
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January 2013 in “Indian Journal of Endocrinology and Metabolism” Women with congenital adrenal hyperplasia have lower fertility, but with proper treatment, they can conceive successfully.
11 citations
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October 2003 in “Postgraduate Medical Journal” Doctors often diagnose Cushing's syndrome late, which worsens symptoms; earlier detection is needed.