research Ovarian leukocyte distribution and cytokine/chemokine mRNA expression in follicular fluid cells in women with polycystic ovary syndrome
Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
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research Molecular basis of hair cell loss
The document concludes that there are no effective clinical treatments for hearing loss due to hair cell damage, but research is ongoing.
research The C3H/HeJ mouse and DEBR rat models for alopecia areata: review of preclinical drug screening approaches and results
Both mouse and rat models are effective for testing alopecia areata treatments.
research Functional enhancement strategies for immunomodulation of mesenchymal stem cells and their therapeutic application
New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.
research Nanoparticles in wound healing from hope to promise from promise to routine
Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.
research The non-neuronal and nonmuscular effects of botulinum toxin: an opportunity for a deadly molecule to treat disease in the skin and beyond
Botulinum toxin has potential for treating various skin conditions and improving wound healing.
research Modeling cell–cell communication for immune systems across space and time
The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.
research Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function
Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.
research The promise and challenges of cell therapy for psoriasis*
Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.
research Mesenchymal Stem Cells From Mouse Hair Follicles Reduce Hypertrophic Scarring in a Murine Wound Healing Model
Mouse stem cells from hair follicles can improve wound healing and reduce scarring.
research Perforins Expression by Cutaneous Gamma Delta T Cells
Gamma delta T cells in the skin help with healing and defense but can also cause autoimmune issues, and more research is needed to understand how they are activated.
research Physiological Doses of Red Light Induce IL ‐4 Release in Cocultures between Human Keratinocytes and Immune Cells
Red light at 627 nm can safely trigger IL-4 release in skin cells, potentially helping treat inflammatory skin conditions.
research Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing
A humanized CXCL12 antibody may delay and treat alopecia areata by altering the immune response.
research The biology and clinical application of systemic glucocorticoids
Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.
research Aberrant inflammasome activation as a driving force of human autoimmune skin disease
Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.
research Alopecia Areata
Understanding the immune-related causes of Alopecia Areata has led to potential treatments like JAK inhibitors.
research Cutaneous drug reactions
Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.
research Cell death as an architect of adult skin stem cell niches
Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.
research Integrated-omics profiling unveils the disparities of host defense to ECM scaffolds during wound healing in aged individuals
Aged individuals heal wounds less effectively due to specific immune cell issues.
research AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasis
AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
research Keratinocytes and Adipose-derived mesenchymal stem cells : The heir and the spare to regenerative cellular therapies for difficult-to-heal skin wounds
Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.
research A human prenatal skin cell atlas reveals immune cell regulation of skin morphogenesis
Immune cells are essential for early hair and skin development and healing.
research Alopecia areata update
Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.
research Role of insulin resistance and diet in acne
Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
research Thymosin β4 Promotes Dermal Healing
Thymosin β4 helps improve skin healing and reduce scarring.
research IMMUNOPATHOLOGY OF THE HUMAN HAIR FOLLICLE
The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.
research Proliferative, lymphocytic, infundibular mural folliculitis and dermatitis with prominent follicular apoptosis and parakeratotic casts in four L abrador retrievers: preliminary description and response to therapy
A new skin disease in four Labrador retrievers responded well to immunosuppressive treatment.
research Adipose and Hair Function: An aPPARent Connection
Fat tissue and a specific protein are crucial for healthy hair growth and maintenance.
research Mechanism of PPARα agonist in alopecia areata
PPARα agonists may help treat alopecia areata by reducing inflammation.
research Fibrosing Alopecia in a Pattern Distribution
FAPD and possibly CCCA may be AGA subtypes, and treatments combining antiandrogens, hair growth agents, hair transplants, and anti-inflammatories could be effective.