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5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Finasteride increases hair weight and count in men with hair loss.

Finasteride effectively reduces hair loss by decreasing androgen levels.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

High doses of finasteride cause cell growth and tumors in mice.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Suppressing certain hormones might help prevent prostate cancer.

Finasteride potentially treats hair loss by reducing DHT production.

PRP injections effectively promote hair growth in androgenetic alopecia patients.

Low-dose finasteride reduces excessive hair growth in teenage girls safely and affordably.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.

Finasteride doesn't affect erections much, but may decrease libido in men.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Finasteride effectively stops hair loss in most patients, but concerns about rare sexual side effects exist.

Testosterone helps human pancreatic cells increase insulin release.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Early diagnosis and treatment, like topical minoxidil, can prevent hair loss in children.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Finasteride negatively affects fish reproduction and gonadal development.