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Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

Hair shaft disorders cause fragile, brittle, and abnormal-looking hair.

Affected males are born with ambiguous genitalia, raised as females, but develop male traits at puberty due to enzyme deficiency.

Monilethrix is linked to a gene cluster on chromosome 12.

Triangular temporal alopecia is a benign hair loss pattern best diagnosed with dermoscopy, with limited treatment options like surgery and hair transplantation.

A boy had a rare scalp condition with thickened skin and different-colored hair.

AMT® is effective and safe for early-stage knee osteoarthritis.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

A man had rare skin tumors with bone formation and cholesterol deposits.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.