76 citations
,
June 2018 in “EMBO Reports” YAP and TAZ proteins are necessary for the development of two types of skin cancer.
75 citations
,
August 2008 in “PLOS ONE” Wnt3a protein, when packed in liposomal vesicles, can stimulate hair growth and could potentially treat conditions like hair loss.
72 citations
,
November 2002 in “Journal of Investigative Dermatology” Estrogen receptor α controls hair growth cycles and skin thickness in male mice.
71 citations
,
June 2005 in “Journal of Investigative Dermatology” PAD enzymes play a key role in hair growth and structure.
68 citations
,
May 2011 in “European Journal of Dermatology” Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.
60 citations
,
December 2005 in “Biomedical Papers” Hair analysis can detect drug use but requires careful interpretation due to its complexity.
57 citations
,
January 2020 in “International Journal of Molecular Sciences” PADs are crucial for healthy skin and hair, and their imbalance can cause skin and hair disorders.
57 citations
,
February 1983 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.
55 citations
,
March 2015 in “Carcinogenesis” WNT10A helps esophageal cancer cells spread and keep renewing themselves.
54 citations
,
January 2007 in “The Journal of Steroid Biochemistry and Molecular Biology” Vitamin D receptor is essential for hair growth and preventing hair loss.
53 citations
,
June 2012 in “Annales d'Endocrinologie” The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.
52 citations
,
November 2003 in “Journal of Investigative Dermatology” Different harmful mutations in the CDH3 gene cause HJMD, but symptoms vary among individuals.
50 citations
,
January 2016 in “The Journal of Clinical Endocrinology and Metabolism” Certain microRNAs in the fluid around eggs are linked to Polycystic Ovary Syndrome and may help diagnose it.
50 citations
,
October 2011 in “Archives of Biochemistry and Biophysics” Vitamin D receptor is essential for healthy hair growth.
47 citations
,
June 2012 in “Genes & Development” A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.
47 citations
,
September 2002 in “Journal of Bone and Mineral Research” A mutation in the vitamin D receptor causes severe resistance to vitamin D, affecting bone health but not hair growth.
45 citations
,
November 2009 in “British Journal of Dermatology” Women with early hair loss have higher blood pressure and aldosterone; screening and treatment may help.
42 citations
,
January 2019 in “Frontiers in Immunology” A blood pressure drug, diltiazem, may also help treat influenza.
38 citations
,
February 2011 in “Annals of Oncology” Men who experienced baldness at age 20 may have double the risk of getting prostate cancer.
37 citations
,
October 2014 in “JAMA dermatology” A woman with severe hair loss was successfully treated with the drug adalimumab.
37 citations
,
April 2011 in “Journal of Biological Chemistry” LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.
36 citations
,
March 2007 in “Journal of Chromatography B” Hair analysis can detect testosterone in horses after drug administration.
35 citations
,
November 1989 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Epitestosterone may act as a weak antiandrogen and can inhibit an enzyme involved in testosterone metabolism.
34 citations
,
August 2012 in “Calcified Tissue International” 34 citations
,
July 2020 in “American journal of human genetics” Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.
33 citations
,
June 2009 in “Journal of Cutaneous Pathology” Erlotinib can cause nonscarring hair loss and itchy skin.
31 citations
,
August 2022 in “Frontiers in Oncology” Photobiomodulation therapy helps manage cancer treatment side effects but needs more research for optimization.
30 citations
,
August 2016 in “Skin research and technology” 3D imaging shows clearer details of skin structure changes with age.
29 citations
,
October 2020 in “eLife” Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.
29 citations
,
February 2010 in “The Journal of Steroid Biochemistry and Molecular Biology” Vitamin D receptor is crucial for healthy hair growth and preventing hair loss.