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February 2017 in “Oncotarget” Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.
31 citations
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January 1981 in “Pharmacology & Therapeutics” Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.
30 citations
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March 2017 in “PLoS ONE” Sulfur slightly improved diet estimates for grizzly bears, but hair growth timing varied, affecting results.
25 citations
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July 2013 in “Environmental Toxicology and Chemistry” Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.
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January 2015 in “Data series” Hurricane Sandy increased contamination in estuarine sediments in New Jersey and New York.
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January 2021 in “Agrobiological Records” Allethrin caused harmful effects and organ damage in rats, worsening with higher doses and longer exposure.
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January 2015 in “Skin pharmacology and physiology” Eating collagen peptides may help with skin and hair growth.
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May 2023 in “Frontiers in immunology” Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.
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June 2025 in “Frontiers in Bioengineering and Biotechnology” Glycopeptide hydrogels are promising for tissue repair, drug delivery, and healing due to their multifunctional properties.
February 2025 in “Journal of Nutrients” Bone broth may improve health and prevent diseases.
January 2025 in “Fitoterapia” Signaling pathways are key targets for developing effective drugs.
Fetal environments contain various chemicals that may disrupt hormones.
No single biomarker is reliable enough for diagnosing and assessing SLE.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.
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December 2007 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.
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March 1998 in “Journal of bone and mineral research” The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
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March 2010 in “Nature Reviews Molecular Cell Biology” MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.
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June 2003 in “Endocrine reviews” Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.
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September 2008 in “Genes & Development” Wnt signaling is vital for cell growth, development, and cancer research.
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January 2012 in “Molecular and Cellular Endocrinology” Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
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January 2005 in “BioEssays” Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
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March 2005 in “Endocrine Reviews” The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
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April 2010 in “Gastroenterology” Targeting colon cancer stem cells might lead to better treatment results.
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January 2017 in “Science” Some wound-healing cells can turn into fat cells around new hair growth in mice.
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May 2007 in “Journal of The American Academy of Dermatology” Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.
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November 2005 in “Journal of Endocrinology” Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
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December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
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November 2009 in “The FASEB Journal” Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.
333 citations
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February 2010 in “Cell Stem Cell” Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
310 citations
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November 2011 in “Environment International” Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.