research Estrogen-Dependent Ontogeny of Sex Differences in Somatostatin Neurons of the Hypothalamic Periventricular Nucleus*
Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.
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research Considerations in genetic counseling of transgender patients: Cultural competencies and altered disease risk profiles
Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.
research Medical Options for Care of Gender Diverse and Transgender Youth
Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.
research Evaluation and Treatment of Gender Dysphoria to Prepare for Gender Confirmation Surgery
The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.
research Recent discoveries and developments of androgen receptor based therapy for prostate cancer
New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.
research Hirsutism, postpartum telogen effluvium, and male pattern alopecia
Hormonal changes during and after pregnancy can cause hair growth changes and hair loss, with treatments available for some conditions.
research MANAGEMENT OF ENDOCRINE DISEASE Hyperandrogenic states in women: pitfalls in laboratory diagnosis
Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.
research A New Paradigm for the Aging Face
Dr. Samuel M. Lam's article concludes that skilled facial fat grafting can effectively restore facial volume and serve as a complement or alternative to traditional face-lifting methods.
research Aesthetic Strategies for the Aging Asian Face
The document suggests using fat grafting and laser therapy to improve the aging Asian face and hair restoration techniques tailored to Asian hair characteristics, emphasizing natural results and cultural sensitivity.
research Alopecia From Oral Contraceptives
Oral contraceptives may cause hair loss in women.
research Assessment of anogenital distance as a diagnostic tool in polycystic ovary syndrome
Measuring the distance from the anus to the clitoris may moderately help diagnose polycystic ovary syndrome, especially in certain cases.
research Targets to treat androgen excess in polycystic ovary syndrome
The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
research Reproductive outcomes of female patients with congenital adrenal hyperplasia due to 21-hydroxylase defi ciency
Women with congenital adrenal hyperplasia have lower fertility, but with proper treatment, they can conceive successfully.
research Journeying Through the Hurdles of Gender-Affirming Care Insurance: A Literature Analysis
Transgender individuals face insurance barriers to gender-affirming surgery, needing policy reforms for better access.
research Dermatologic care of sexual and gender minority/LGBTQIA youth, Part 2: Recognition and management of the unique dermatologic needs of SGM adolescents
Pediatric dermatologists need to understand the unique skin health needs of LGBTQIA youth to provide better care.
research Thyroid hormones and androgens differentially regulate gene expression in testes and ovaries of sexually mature Silurana tropicalis
Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.
research Cultural Sensitivity and Challenges in Management of the Transgender Patient With ESRD in Transplantation
Healthcare providers need better understanding and cultural sensitivity to improve care for transgender patients with kidney failure needing transplants.
research Hirsutism in the Adolescent Female
The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.
research Polymorphisms in androgen and estrogen receptor genes: effects on male aging
Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.
research Effects of hormonal treatment on dermatological outcome in transgender people: a multicentric prospective study (ENIGI)
Hormonal treatments can change hair and skin in transgender people, but may not fully achieve desired results.
research Intracrine Testosterone Activation in Human Pancreatic β-Cells Stimulates Insulin Secretion
Testosterone helps human pancreatic cells increase insulin release.
research Influence of Genotype and Hyperandrogenism on Sexual Function in Women With Congenital Adrenal Hyperplasia
Women with nonclassic congenital adrenal hyperplasia experience more sexual dysfunction and distress.
research Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Sexual Function and Depressive Symptoms in Young Women With Nonclassic Congenital Adrenal Hyperplasia
Young women with nonclassic congenital adrenal hyperplasia may experience worse sexual function and mild depression compared to healthy women.
research The Safety of Testosterone Therapy in Women
Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.
research Hyperandrogenism from an Ovarian Interstitial-Cell Tumor in an Alpaca
An alpaca acted like a male and couldn't have babies because of a benign tumor in its ovary that caused high testosterone levels.
research The effects of oestrogens on linear bone growth
Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.
research Predominant expression of 5 alpha-reductase type 1 in pubic skin from normal subjects and hirsute patients.
The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.
research Repurposing steroidogenesis inhibitors for the therapy of neuropsychiatric disorders: Promises and caveats
Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.
research Recommendations of endocrine treatment for patients with gender dysphoria
The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.