research The Human Skin Microbiome in Selected Cutaneous Diseases
Changes in skin microbes play a role in some skin diseases and could lead to new treatments.
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research Oxidative stress management in the hair follicle: Could targeting NRF2 counter age‐related hair disorders and beyond?
Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
research Pathophysiology of the Burn Scar
Burn scars heal abnormally and more research is needed to find better treatments.
research Molecular mechanisms of androgenetic alopecia
AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.
research Androgenetic alopecia and microinflammation
Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
research Influence of TRPV3 mutation on hair growth cycle in mice
The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.
research Dupilumab: A Review of Present Indications and Off-Label Uses
Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.
research A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention
Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.
research Mammalian Fetal Organ Regeneration
Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.
research Tumor Promotion in Skin: Are Active Oxygen Species Involved?
Active oxygen species might be involved in skin tumor growth, but their exact role is unclear.
research Anti-inflammatory and anti-hyperplastic effect of Bazhengsan in a male rat model of chronic nonbacterial prostatitis
Bazhengsan reduces inflammation and tissue growth in chronic prostatitis.
research Proprietary Herbal Extract Downregulates the Gene Expression of Il-1 and #945; in HaCaT Cells: Possible Implications Against Nonscarring Alopecia
A herbal extract may help treat certain types of hair loss by reducing a specific gene's activity.
research Drug-induced skin reactions: a pathologist viewpoint
Some drugs can cause skin reactions, which may improve when the drug is stopped, and rapid diagnosis and stopping the drug is crucial.
research Scarless wound healing – a literature review
Fetal skin can heal without scarring, offering insights for new scar-reducing treatments.
research Lichen planus – A refractory autoimmune disorder
Lichen planus is a chronic autoimmune disease that is hard to treat and more common in women.
research PAK4 signaling in health and disease: defining the PAK4–CREB axis
PAK4 is crucial in cancer progression, brain development, and could be a therapeutic target, especially through the PAK4-CREB axis.
research Use of H-1 Antihistamine in Dermatology: More than Itch and Urticaria Control: A Systematic Review
H-1 antihistamines may help with various skin conditions, but more research is needed to confirm their effectiveness.
research Structure and Function of the Skin
The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.
research A guide to studying human dermal adipocytes in situ
The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
research Estrogens and the hair follicle. Ostrogene und der Haarfollikel
Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.
research A nude mouse model of hypertrophic scar shows morphologic and histologic characteristics of human hypertrophic scar
Nude mice with grafted human skin developed scars similar to human hypertrophic scars.
research Illuminating microflora: shedding light on the potential of blue light to modulate the cutaneous microbiome
Blue light might help treat skin conditions by affecting the skin's bacteria.
research The coenzyme A precursor pantethine enhances antitumor immunity in sarcoma
Pantethine may boost the immune system's ability to fight sarcoma.
research Past and Future Strategies for GPCR Deorphanization
Finding functions for unknown GPCRs is hard but key for making new drugs.
research The Potential Application of Exosomes as Therapeutic Agents, Carriers, and Biomarkers in Skin Diseases
Exosomes could revolutionize skin disease treatment and healing.
research AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasis
AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
research Tregs: Where We Are and What Comes Next?
The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
research The role of multiomics in revealing the mechanism of skin repair and regeneration
Multiomics helps understand and improve skin healing and repair.
research A Guide to Studying Human Hair Follicle Cycling In Vivo
The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.
research Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists
Formyl-peptide receptor agonists could be new anti-inflammatory drugs.