research Female Hirsutism: Pathophysiological Considerations and Therapeutic Implications*
Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
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research Percutaneous Absorption of Minoxidil in Man
Minoxidil absorbs poorly through skin, with low risk of side effects at 1-2% concentration.
research Prolactin: an emerging force along the cutaneous–endocrine axis
Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
research Effect of constant-release melatonin implants and prolonged exposure to a long day photoperiod on prolactin secretion and hair growth in mouflon (Ovis gmelini musimon)
Melatonin implants and long daylight hours alter the timing of hormone release and hair growth in mouflon sheep.
research 5α-Reduced glucocorticoids: a story of natural selection
Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.
research Adverse Event Reporting in Clinical Trials of Finasteride for Androgenic Alopecia: A Meta-analysis.
Finasteride for hair loss may cause long-lasting side effects like impotence and low libido, but trials lack proper safety reporting.
research Effective medical treatment for common baldness in women
Antiandrogen therapy helped increase hair growth in women with hormonal imbalances related to baldness.
research Autophagy is essential for maintaining the growth of a human (mini-)organ: Evidence from scalp hair follicle organ culture
Autophagy is important for human hair growth and health.
research Polycystic Ovary Syndrome and Its Differential Diagnosis
The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.
research The nocebo effect: A clinicians guide
Negative expectations can cause adverse effects in patients even without active treatment, and managing this nocebo effect involves better communication and patient-clinician relationships.
research Recent advances in oxasteroids chemistry
New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.
research Chronic Stress Suppresses the Expression of Cutaneous Hypothalamic–Pituitary–Adrenocortical Axis Elements and Melanogenesis
Chronic stress can reduce skin pigmentation.
research Fluoroquinolone-induced serious, persistent, multisymptom adverse effects
Some people experience severe, long-lasting side effects from fluoroquinolone antibiotics, leading to the recommendation of limited use and increased awareness of these risks.
research Doping-Control Analysis of the 5α-Reductase Inhibitor Finasteride: Determination of Its Influence on Urinary Steroid Profiles and Detection of Its Major Urinary Metabolite
Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.
research Clinical efficacy and safety of low‐dose flutamide alone and combined with an oral contraceptive for the treatment of idiopathic hirsutism
Low-dose flutamide helps reduce excessive hair growth and is even more effective with birth control, without bad effects on blood fats.
research Case 4-2012
Early diagnosis and treatment of TPP can prevent complications.
research Repurposing existing drugs for COVID-19: an endocrinology perspective
Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
research Cepharanthine, a regulator of keap1-Nrf2, inhibits gastric cancer growth through oxidative stress and energy metabolism pathway
Cepharanthine may help treat gastric cancer by causing cancer cell death and affecting energy use.
research ANTIANDROGEN THERAPY IN DERMATOLOGY
Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.
research Autoimmune polyendocrine syndrome type 1: an Italian survey on 158 patients
APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.
research Human hair follicles operate an internal Cori cycle and modulate their growth via glycogen phosphorylase
Inhibiting glycogen metabolism can promote hair growth.
research ANDROGENETIC ALOPECIA
Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.
research What does acne genetics teach us about disease pathogenesis?
Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.
research Possible contribution of chronobiology to cardiovascular health
Understanding and tracking our body's natural daily rhythms could help improve heart health.
research Comparative Evaluation of Biomarkers of Inflammation Among Indian Women With Polycystic Ovary Syndrome (PCOS) Consuming Vegetarian vs. Non-vegetarian Diet
Vegetarian Indian women with PCOS have higher inflammation levels than non-vegetarians.
research Exercise activates the PI3K-AKT signal pathway by decreasing the expression of 5α-reductase type 1 in PCOS rats
Exercise improves insulin sensitivity and hormone regulation in PCOS rats.
research Hedonic sensitivity to natural rewards is affected by prenatal stress in a sex-dependent manner
Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.
research Lupus panniculitis clinically simulating alopecia areata
Lupus can look like hair loss from alopecia areata but needs different treatment.
research Study of gene expression alteration in male androgenetic alopecia: evidence of predominant molecular signalling pathways
Hair loss involves immune responses, inflammation, and disrupted signaling pathways.
research Revisiting hyper- and hypo-androgenism by tandem mass spectrometry
The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.