research A preliminary study of markers for human hair follicle melanin stem cell
Researchers identified potential markers for human hair color stem cells.
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research 1272 p21Waf1/Cip1 is differentially expressed in epidermal versus follicular melanocytes and melanoma cells and is phenotypically regulated by UVB-mediated apoptosis
The protein p21 is more abundant in normal skin cells than in melanoma cells and may help protect against melanoma, with UVB light affecting its levels.
research さまざまな臓器からの培養線維芽細胞による毛包誘導
Cells from skin and lung can help regenerate hair follicles.
research Dual effects of human adipose tissue-derived mesenchymal stem cells in human lung adenocarcinoma A549 xenografts and colorectal adenocarcinoma HT-29 xenografts in mice
Stem cells slowed lung tumor growth but increased colon tumor growth in mice.
research CRISPR/Cas9-Mediated Generation of COL7A1-Deficient Keratinocyte Model of Recessive Dystrophic Epidermolysis Bullosa.
Scientists created a cell model to study and find treatments for a skin disease called RDEB.
research A Murine Monoclonal Antibody (VM-1) Against Human Basal Cells Inhibits the Growth of Human Keratinocytes in Culture
research Functional analysis of thymosin beta-4 using over-expressing transgenic mice
Melanoma cells lose their ability to form tumors when placed in a zebrafish embryo environment.
research Development of 3-D Microbioreactor Systems for Cell-Based High Throughput Screening
A new 3-D bioreactor system improves drug screening and reduces animal testing.
research Establishment of keratinocyte cell lines from human hair follicles
Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.
research Decision letter: Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium
Skin cells can naturally limit the growth of cancerous changes by balancing cell renewal and differentiation.
research Maintenance of high proliferation and multipotent potential of human hair follicle-derived mesenchymal stem cells by growth factors
Growth factors help hair follicle stem cells grow and stay versatile.
research Single-cell RNA-seq highlights heterogeneity in human primary Wharton’s jelly mesenchymal stem/stromal cells cultured in vitro
Wharton's jelly stem cells show diverse traits and functions.
research Merkel cell differentiation in trichoblastoma
Trichoblastomas may mimic fetal skin development by having many Merkel cells, unlike adult skin.
research Generation and Characterization of Multipotent Stem Cells from Established Dermal Cultures
Human skin cells can be turned into versatile stem cells, but their ability to do so decreases with repeated use.
research 85 Primary cutaneous follicle center lymphoma spans yet unrecognised subtypes including polyclonal reactions
PCFCL may have unrecognized subtypes and needs more research.
research Use of Single‐Cell Data and scPagwas Analysis to Identify T Cell Subsets and Construct a Prognostic Model for Clear Cell Renal Cell Carcinoma
T cell subsets are crucial in kidney cancer, and a new model predicts patient outcomes using key genes.
research THE INSUSCEPTIBILITY OF C57 BLACK MICE TO POST-IRRADIATION LEUKEMIA, SOME UNREPORTED POST-IRRADIATION CHANGES
CXCL7 is essential for muscle repair by aiding early neutrophil infiltration.
research Differentiation capacity of stromal fibroblast-like cells from human bone marrow, adipose tissue, hair follicle dermal papilla and derma
research Changes in the proteomic profile of adipose tissue-derived mesenchymal stem cells during passages
Adipose stem cells show common protein changes as they grow, especially involving S100A6.
research A computational modelling framework to quantify the effects of passaging cell lines
Cell characteristics change with passage numbers, affecting experiment results.
research Fibroblast heterogeneity and functions: insights from single-cell sequencing in wound healing, breast cancer, ovarian cancer and melanoma
Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.
research Bioinformatics analysis and verification of m6A related genes based on the construction of keloid diagnostic model
IGF2BP3 and other m6A-related genes are linked to keloid formation and could be potential treatment targets.
research Regeneration of Mouse Skin Melanocyte Stem Cells In Vivo and In Vitro
The research found ways to activate melanocyte stem cells for potential treatment of skin depigmentation conditions.
research Screening and culture of human vaginal mucosa stem cells
Vaginal mucosa stem cells can be effectively isolated and cultured using specific methods.
research REV7: a small but mighty regulator of genome maintenance and cancer development
REV7 is crucial for genome stability and cancer treatment, making it a potential target for therapy.
research Direct conversion of mouse and human fibroblasts to functional melanocytes by defined factors
Fibroblasts can be turned into melanocytes for potential skin treatments.
research Development of a FRET-based 3D in vitro breast tumor model and its application in evaluating drug-induced apoptosis
A new 3D breast tumor model helps test drug effects more accurately than traditional methods.
research Distinct transcriptomic landscapes of cutaneous basal cell carcinomas and squamous cell carcinomas
Human basal cell carcinomas and squamous cell carcinomas have unique gene expression patterns not fully mirrored in mouse models.
research Culture and characterization of rat hair follicle stem cells
Rat hair follicle stem cells can be successfully cultured and may be useful for creating tissue-engineered hair, vessels, and skin.
research Mitochondrial-related genes as prognostic and metastatic markers in breast cancer: insights from comprehensive analysis and clinical models
Mitochondrial genes help predict breast cancer outcomes and spread.