research Newly born mesenchymal cells disperse through a rapid mechanosensitive migration
Newly born mesenchymal cells quickly spread out in response to tissue tension during early development.
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120-150 / 1000+ results research Signaling pathways involved in hair follicle cycling and morphogenesis
Hair growth and development are controlled by complex signaling pathways.
research TRPA1 Modulates Mechanotransduction in Cutaneous Sensory Neurons
TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.
research Reviewer #3 (Public Review): Spatiotemporal dynamics of sensory neuron and Merkel-cell remodeling are decoupled during epidermal homeostasis
Sensory neuron changes and Merkel-cell changes in the skin happen independently during normal skin maintenance.
research Mesenchymal Meis2 controls whisker development independently from trigeminal sensory innervation
Meis2 is essential for whisker development, independent of nerve involvement.
research An eGFP-Col4a2 mouse model reveals basement membrane dynamics underlying hair follicle morphogenesis
Basement membrane changes are crucial for hair follicle development.
research Epidermal–dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures
Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
research Spatiotemporal dynamics of sensory neuron and Merkel-cell remodeling are decoupled during epidermal homeostasis
Merkel cells stabilize nerve endings in the skin, and they change independently of each other.
research Transcriptome analyses of reprogrammed feather / scale chimeric explants revealed co-expressed epithelial gene networks during organ specification
Key genes can rewire networks, changing skin appendage types.
research Parallels in signaling between development and regeneration in ectodermal organs
research Dynamics of Merkel Cell Patterns in Developing Hair Follicles in the Dorsal Skin of Mice, Demonstrated by a Monoclonal Antibody to Mouse Keratin 8
Merkel cells develop independently of nerves and are linked to specific hair follicles in mice.
research Spatiotemporal dynamics of sensory neuron and Merkel-cell remodeling are decoupled during epidermal homeostasis
Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.
research Expression of Signaling Components in Embryonic Eyelid Epithelium
Eyelid cells share signaling components but differ in pathway activity.
research 439 Gradients of Mesenchymal Stiffness Control Sweat Gland Cell Fate Specification During Morphogenesis
Mesenchymal stiffness affects sweat gland cell development.
research Wnt signaling modulates mechanotransduction in the epidermis to drive hair follicle regeneration
Wnt signaling helps regenerate hair follicles by affecting how skin cells sense and respond to mechanical forces.
research Retinoic Acid and Mouse Skin Morphogenesis. II. Role of Epidermal Competence in Hair Glandular Metaplasia
Retinoic acid causes gland formation instead of hair in mouse skin by altering epidermal and dermal interactions.
research Tactile sensitivity in the rat: a correlation between receptor structure and function
Rats have different touch receptors in their paws that help with movement and handling objects.
research 329 In vitro co-culture models of merkel cell-neurite complex in touch domes
The study concluded that the developed models are effective for studying hair growth mechanisms and testing new treatments.
research Localization of mechanosensitive channel TRPV4 in mouse skin
TRPV4 helps sense pressure in mouse skin.
research Mechanotransduction unifies healthy non-diabetic wound healing over time by promoting a Cd14+/C1qa+ fibroblast subpopulation
Mechanotransduction aids healthy wound healing by promoting specific fibroblasts.
research Localisation of members of the notch system and the differentiation of vibrissa hair follicles: Receptors, ligands, and fringe modulators
Notch-related genes play a key role in the development and cycling of hair follicles.
research In vitro interactions between sensory nerves, epidermis, hair follicles and capillaries in a tissue‐engineered reconstructed skin
The model effectively studies how sensory nerves interact with skin components, aiding research on wound healing and hair growth.
research Molecular biology of hair morphogenesis: Development and cycling
Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.
research 1412 “Telescope model” for coordinated organ morphogenesis and stem cell formation
Developing hair follicles form from ring-shaped patterns, with future stem cells originating from the outer ring, not the upper layers, as previously thought.
research [Genetic expression and morphogenesis of the skin in vertebrates].
Retinoic acid can change skin structures in vertebrates, like turning scales into feathers or hair buds into glands.
research Self‐organizing hair peg‐like structures from dissociated skin progenitor cells: New insights for human hair follicle organoid engineering and Turing patterning in an asymmetric morphogenetic field
Researchers created early-stage hair-like structures from skin cells, showing how these cells can self-organize, but more is needed for complete hair growth.
research Growth of Nerve Fibers to Merkel Cells Observed in Co-Culture of Sensory Ganglia and Sinus Hair Follicles
Merkel cells likely attract sensory nerve fibers.
research Molecular Regulatory Mechanisms in Chicken Feather Follicle Morphogenesis
The document concludes that various signaling pathways and genetic factors are crucial for chicken feather development, affecting poultry quality.
research 1407 Mechanical force activation of TGF-β signaling controls hair follicle regression
Muscle around hair follicles controls hair loss by releasing a signal that causes cell death.