18 citations
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April 2002 in “Journal of cutaneous pathology” Tiny infundibular cysts are the main lesions in chloracne, not comedones.
18 citations
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April 1989 in “Archives of Dermatology” Iron deficiency can cause hair color changes, which can be reversed with iron supplements.
17 citations
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May 2007 in “Forensic Science Medicine and Pathology” Clozapine levels in hair reflect dosage and bind more to pigmented hair.
17 citations
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April 2023 in “ACS Biomaterials Science & Engineering” Silk fibroin microneedles can effectively treat vitiligo by promoting skin pigmentation.
16 citations
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February 2015 in “Photochemistry and Photobiology” Hair acts as a significant natural sun barrier, with protection increasing based on hair density, thickness, and melanin presence.
16 citations
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January 2008 in “Acta dermato-venereologica” Vitamin B12 deficiency can cause skin darkening and increased blood vessels, but treatment can improve symptoms.
15 citations
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January 2017 in “Pigment International” Early hair graying is often inherited and influenced by genetics, environment, and lifestyle, but treatment options are limited.
15 citations
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December 2016 in “Advanced Pharmaceutical Bulletin” The new cream with N-acetyl glucosamine didn't change skin color after 8 weeks.
15 citations
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June 2015 in “Lasers in Medical Science” The 830-nm wavelength was most effective at promoting hair growth in rats using low-level laser therapy.
15 citations
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March 2015 in “Experimental Dermatology” Clotrimazole, an antifungal cream, may safely reduce skin pigmentation by breaking down the enzyme needed for making melanin.
15 citations
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June 1986 in “Pediatric Dermatology” Androgens increase pigmentation in young hamsters, but estrogens can reverse this effect.
14 citations
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April 2007 in “Journal of aging and health” Balding men had lower bone density, while balding women had higher hip bone density.
14 citations
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April 2005 in “Experimental Dermatology” Stressed fibroblasts greatly increase melanin production in hair, skin, and eye cells, mainly due to a growth factor called bFGF.
14 citations
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May 2016 in “International Journal of Molecular Sciences” PP2Acα is essential for proper hair and skin development.
13 citations
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July 2024 in “Medicina” Lasers can trigger skin reactions, especially in darker skin, and more research is needed to improve treatments.
13 citations
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September 2023 in “Molecules” Liposomal coffee berry extract improves skin elasticity and reduces melanin better than regular extract.
12 citations
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May 2023 in “EMBO reports” High mTORC1 activity slows hair growth and causes it to lose color.
12 citations
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May 2019 in “Journal of cosmetic dermatology” Effective treatments for premature hair graying still require significant research.
12 citations
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December 1981 in “Journal of Endocrinology” α-MSH increases melanin production in moulting hair follicles, while AVT inhibits it.
11 citations
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February 2018 in “Archives of Pharmacal Research” Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.
11 citations
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January 2016 in “Evidence-based Complementary and Alternative Medicine” Rice bran extract can increase melanin production and may help treat melanin deficiency.
11 citations
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January 1990 in “Cell and Tissue Research” Minoxidil does not specifically target any hair follicle cells.
10 citations
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January 2012 in “Journal of biomedical optics” Melanin density affects hair color, and this method can help in cosmetic assessments and diagnosing hair diseases.
10 citations
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January 2000 in “Journal Of Cutaneous Laser Therapy” Laser hair removal might also work by damaging blood vessels around hair follicles.
10 citations
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April 2022 in “Critical reviews in food science and nutrition” Skin odorant receptors respond to flavors and could be targeted to improve skin health and treat diseases.
10 citations
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May 2012 in “PloS one” Low ERCC3 gene activity is linked to non-pigmented hair growth.
10 citations
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June 1999 in “Veterinary Dermatology” Two cows had a rare hair disorder causing hair loss but were otherwise healthy.
10 citations
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September 1994 in “International Journal of Dermatology” Three Iranian men had reddish-brown facial pigmentation with no effective treatment.
9 citations
,
April 2019 in “Dermatologic Therapy” The 1,064-nm Nd:YAG laser is versatile and effective for treating leg veins, hair removal, and skin rejuvenation, especially in darker skin types.
9 citations
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June 2017 in “The American journal of dermatopathology/American journal of dermatopathology” The study found increased skin pigmentation and variable melanocyte density in a patient with Addison's disease.